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兔 anti-小鸡 IgY Antibody (Biotin)

WB, IHC (p) Polyclonal IgG Biotin
产品编号 ABIN5662630
发货至: 中国
  • 抗原 See all IgY products
    IgY
    适用
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    小鸡
    宿主
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    标记
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    Biotin
    应用范围
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Purified by Protein A.
    免疫原
    Chicken IgY
    亚型
    IgG
  • 应用备注
    WB 1:500-2000
    IHC-P 1:500-2000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Aliquot to Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20°C
    有效期
    12 months
  • Ren, Wang, Ma, Yuan, Zhang, Yu, Hao: "Arnebia preventing the expression of Muc1 protein decrease results in anti-implantation in early pregnant mice." in: Contraception, Vol. 83, Issue 4, pp. 378-84, (2011) (PubMed).

  • 抗原
    IgY
    Abstract
    IgY 产品
    物质类
    Antibody
    背景

    In chickens, immunoglobulin Y is the functional equivalent to Immunoglobulin G (IgG). Like IgG, it is composed of two light and two heavy chains. Structurally, these two types of immunoglobulin differ primarily in the heavy chains, which in IgY have a molecular mass of about 65,100 atomic mass units (amu), and are thus larger than in IgG. The light chains in IgY, with a molar mass of about 18,700 amu, are somewhat smaller than the light chains in IgG. The molar mass of IgY thus amounts to about 167,000 amu. The steric flexibility of the IgY molecule is less than that of IgG.Functionally, IgY is partially comparable to Immunoglobulin E (IgE), as well as to IgG. However, in contrast to IgG, IgY does not bind to Protein A, to Protein G, or to cellular Fc receptors. Furthermore, IgY does not activate the complement system. The name Immunoglobulin Y was suggested in 1969 by G.A. Leslie and L.W. Clem, after they were able to show differences between the immunoglobulins found in chicken eggs, and immunoglobulin G. Other synonymous names are Chicken IgG, Egg Yolk IgG, and 7S-IgG.

    Synonyms: Egg yolk immunoglobulin, IgY.

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