小鼠 anti-人 IgE (Chain epsilon) Antibody
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北京 101111
Quick Overview for 小鼠 anti-人 IgE (Chain epsilon) Antibody (ABIN492642)
抗原
克隆类型
应用范围
克隆位点
亚型
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抗原表位
- Chain epsilon
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适用
- 人
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宿主
- 小鼠
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纯化方法
- Purified
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应用备注
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ELISA (Recommended as a Detection Antibody). Western blotting. Dot- and slot-immunoblotting. Immunocytochemistry. Immunohistochemistry on Frozen Sections.
Other applications not tested.
Otimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- 100 mM Borate buffered saline, pH 8.2 without preservatives or amine-containing buffer salts.
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储存液
- Without preservative
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注意事项
- Monoclonal antibodies should not be stored at a temperature below -25 °C due to the aggregation effect of the protein.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C
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- IgE
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物质类
- Antibody
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背景
- IgE is typically the least abundant isotype - blood serum IgE levels in a normal ("non-atopic") individual are ~150 ng/mL, compared to 10 mg/mL for the IgGs - it is capable of triggering the most powerful immune reactions. Most of our knowledge of IgE has come from research into the mechanism of a form of allergy known as type 1 hypersensitivity. There is much speculation into what physiological benefits IgE contributes, and so far, circumstantial evidence in animal models and statistical population trends have hinted that IgE may be beneficial in fighting gut parasites such as Schistosoma mansoni, but this has not been conclusively proven in humans. IgE may play an important role in the immune system's recognition of cancer, in which the stimulation of a strong cytotoxic response against cells displaying only small amounts of early cancer markers would be beneficial. IgE may be an important target in treatments for allergy and asthma.Synonyms: Immunoglobulin E human
抗原
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