小鼠 anti-人 IgM (Chain mu), (Fab Region) Antibody
IF, EIA, Func
Monoclonal
UHB
IgG3
unconjugated
1 image
产品编号 ABIN371468
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for 小鼠 anti-人 IgM (Chain mu), (Fab Region) Antibody (ABIN371468)
抗原
IgM
克隆类型
单克隆
应用范围
Immunofluorescence (IF), Enzyme Immunoassay (EIA), Functional Studies (Func)
克隆位点
UHB
亚型
IgG3
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抗原表位
- Chain mu, Fab Region
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适用
- 人
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宿主
- 小鼠
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纯化方法
- Purified
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应用备注
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Human B Cell Stimulation: < / = 10 μg/mL.
Other applications not tested.
Otimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.25 mg/mL
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缓冲液
- Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -28 °C for longer.
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- IgM
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物质类
- Antibody
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背景
- IgM normally constitutes about 10 % of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences. IgM measurement yields information about the body's immediate resistance and response to infection as well as information related to specific diseases. Decreased levels are associated with immune deficiency states, hereditary deficiencies, and myeloma. Increased levels can be associated with Waldenstrom's macroglobulinemia, chronic infection and hepatocellular disease.Synonyms: Human Immunoglobulin M
抗原
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