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兔 anti-人 Ig (Chain kappa) Antibody

IHC, IHC (p) Polyclonal unconjugated
产品编号 ABIN336978
发货至: 中国

Quick Overview for 兔 anti-人 Ig (Chain kappa) Antibody (ABIN336978)

抗原

Ig

克隆类型

  • 122
  • 95
多克隆

应用范围

  • 173
  • 138
  • 100
  • 69
  • 57
  • 26
  • 22
  • 12
  • 12
  • 7
  • 6
  • 6
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 79
    • 78
    • 63
    • 38
    • 4
    • 2
    • 1
    Chain kappa

    适用

    • 117
    • 63
    • 20
    • 18
    • 9
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 猴

    宿主

    • 102
    • 77
    • 38
    • 18
    • 3
    • 1
    • 1

    特异性

    Molecular Weight: 25 kDa.

    免疫原

    Purified human Kappa light chain from human Bence Jones proteins
  • 应用备注

    IHC, ICC (frozen or formalin–fixed paraffin-embedded (FFPE) tissue sections, cell smears) 1:50-1:200 using streptavidin-Biotin system or polymer system. Prediluted antibody is used directly without dilution. FFPE tissue sections require antigen retriever (boiling tissue in 10 mM citrate pH 6.0 for 10-20 minutes, followed by cooling at RT for 15-20 minutes). The optimum dilution should be determined by the individual lab. Positive Control: Human tonsil. Cellular Localization: Cytoplasmic.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The antibody is supplied with 1% BSA in PBS with 0.05% azide, pH 7.4. The Prediluted antibody is supplied in our Universal antibody dilution buffer (AR-6526) green in color.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • 抗原

    Ig

    别名

    Immunoglobulin Ig

    背景

    Human Kappa chain is a 25 kDa light chain present on all 5 immunoglobulin’s (IgA,IgG, IgM, IgD, and IgE) and is also present in free form. Kappa and Lambda light chains consists of a variable region and a constant region and can be easily be differentiated by the antigenic properties of a constant region. The ratio of Kappa to Lambda chain is 70:30, most of them are bound to heavy chains of immunoglobulin. This antibody is useful in identification of leukemias, plasmasacytomas and certain non-Hodgkin’s lymphomas. In normal human serum lambda chains are present 1.6-15.2 mg/ml. In multiple myeloma or B-cell malignancies these levels are increased. Higher amounts are also present in Bence Jones patient’s urine.
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