小鼠 anti-人 lambda (Light Chain) Antibody
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北京 101111
Quick Overview for 小鼠 anti-人 lambda (Light Chain) Antibody (ABIN3026854)
抗原
克隆类型
应用范围
质量等级
克隆位点
亚型
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抗原表位
- Light Chain
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适用
- 人
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宿主
- 小鼠
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原理
- Lambda Antibody (azide and preservative free)
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产品特性
- This mAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
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纯化方法
- Protein G affinity chromatography
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免疫原
- Purified human lambda light chain was used as the immunogen for this Lambda antibody.
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Mouse anti-Human lambda (Chain lambda) antibody
FACS, ELISA Monoclonal JDC-12 IgG1 unconjugated
Goat anti-Human lambda antibodyFACS, ELISA, IHC (p), WB, ICC, ELISpot, IP, St, SPR Polyclonal IgG unconjugated
Goat anti-Human lambda antibody (Alkaline Phosphatase (AP))ELISA, IHC (p), WB, ICC, ELISpot Polyclonal IgG Alkaline Phosphatase (AP)
Goat anti-Human lambda antibody (HRP)ELISA, IHC (p), WB, ICC, ELISpot Polyclonal IgG HRP
Goat anti-Human lambda antibody (Biotin)FACS, ELISA, IHC (p), WB, ICC, ELISpot, IP Polyclonal IgG Biotin
Mouse anti-Human lambda antibody (Alkaline Phosphatase (AP))ELISA, WB Monoclonal JDC-12 IgG1 Alkaline Phosphatase (AP)
Mouse anti-Human lambda antibody (HRP)ELISA, WB Monoclonal JDC-12 IgG1 HRP
Goat anti-Human lambda antibody (Biotin) - PreadsorbedFACS, ELISA Polyclonal IgG Biotin
Goat anti-Human lambda antibodyFACS, ELISA, WB, St Polyclonal IgG unconjugated F(ab')2 fragment
Goat anti-Human lambda antibody (Alkaline Phosphatase (AP)) - PreadsorbedELISA Polyclonal IgG Alkaline Phosphatase (AP)
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应用备注
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The optimal dilution of the Lambda antibody for each application should be determined by the researcher.
1. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Lambda antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- lambda
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背景
- This mAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with kappa light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
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UniProt
- P01701
抗原
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