小鼠 anti-人 IgD Antibody
(6 references)Quick Overview for 小鼠 anti-人 IgD Antibody (ABIN2749203)
抗原
克隆类型
应用范围
克隆位点
亚型
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适用
- 人
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宿主
- 小鼠
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原理
- Anti-Hu IgD Purified
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特异性
- The mouse monoclonal antibody IA6-2 recognizes human immunoglobulin D.
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交叉反应 （详细）
- Human
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- Human IgD
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Mouse anti-Human IgD antibody (APC)
FACS Monoclonal IA6-2 IgG2a kappa APC
Mouse anti-Human IgD antibody (PE)FACS Monoclonal IA6-2 IgG2a kappa PE
Goat anti-Human IgD antibody (PE)FACS, ELISA Polyclonal IgG PE
Mouse anti-Human IgD antibody (Biotin)FACS, ELISA Monoclonal IADB6 IgG2a Biotin
Mouse anti-Human IgD antibody (FITC)FACS, ELISA Monoclonal IADB6 IgG2a FITC
Goat anti-Human IgD antibody (PE)FACS, ELISA Polyclonal IgG PE F(ab')2 fragment
Goat anti-Human IgD (Heavy Chain) antibodyFACS, ELISA, WB Polyclonal IgG unconjugated
Goat anti-Human IgD antibodyFACS, ELISA Polyclonal IgG unconjugated F(ab')2 fragment
Goat anti-Human IgD (Heavy Chain) antibody (FITC)FACS, ELISA Polyclonal IgG FITC
Goat anti-Human IgD (Heavy Chain) antibody (Biotin)FACS, ELISA, WB Polyclonal IgG Biotin
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应用备注
- Flow cytometry: Recommended dilution: 2-4 μg/mL.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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: "Characterization of antigen-specific B cells using nominal antigen-coated flow-beads." in: PLoS ONE, Vol. 8, Issue 12, pp. e84273, (2014) (PubMed).
: "Decreased CD5⁺ B cells in active ANCA vasculitis and relapse after rituximab." in: Clinical journal of the American Society of Nephrology : CJASN, Vol. 8, Issue 3, pp. 382-91, (2013) (PubMed).
: "Immunoglobulin M memory B cell decrease in inflammatory bowel disease." in: European review for medical and pharmacological sciences, Vol. 8, Issue 5, pp. 199-203, (2005) (PubMed).
: "Regulation of inherently autoreactive VH4-34 B cells in the maintenance of human B cell tolerance." in: The Journal of clinical investigation, Vol. 108, Issue 7, pp. 1061-70, (2001) (PubMed).
: "Mutations of CD40 gene cause an autosomal recessive form of immunodeficiency with hyper IgM." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 22, pp. 12614-9, (2001) (PubMed).
: "Immunogenic targeting of recombinant peptide vaccines to human antigen-presenting cells by chimeric anti-HLA-DR and anti-surface immunoglobulin D antibody Fab fragments in vitro." in: Journal of virology, Vol. 69, Issue 4, pp. 2357-65, (1995) (PubMed).
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: "Characterization of antigen-specific B cells using nominal antigen-coated flow-beads." in: PLoS ONE, Vol. 8, Issue 12, pp. e84273, (2014) (PubMed).
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- IgD
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物质类
- Antibody
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背景
- Immunoglobulin D (IgD) is expressed on the surface of naive mature B cells, thus later than IgM, and is coexpressed with it then. Triggered by antigen binding, it signals through the CD79 complex to activate the B cells. Expression of IgD is lost after the isotype switch. Soluble IgD is present in very small amounts in the serum. IgD can bind to basophils and mast cells to activate them in an IgE-independent way to participate in respiratory immune defense.,Immunoglobulin D
抗原
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