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小鼠 anti-小鼠 IgG2ab, Subclass Specific Antibody (Biotin)

ELISA, FACS Monoclonal 5-7 IgG3 kappa Biotin
产品编号 ABIN2689675
发货至: 中国
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Quick Overview for 小鼠 anti-小鼠 IgG2ab, Subclass Specific Antibody (Biotin) (ABIN2689675)

抗原

IgG2ab (IgG2ab, Subclass Specific)

克隆类型

  • 9
单克隆

标记

  • 3
  • 2
  • 2
  • 1
  • 1
Biotin

应用范围

  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
ELISA, Flow Cytometry (FACS)

克隆位点

5-7

亚型

IgG3 kappa
  • 适用

    小鼠

    宿主

    • 8
    • 1
    小鼠

    产品特性

    This antibody reacts specifically with mouse IgG2a of Igh-C [b] haplotype (e.g., C57BL/6, C57BL/10, NOD, SJL). It has been reported not to react with IgG2a of the a, c, d, e, f, g, h, j, n, o, or p haplotypes (e.g., A, AKR, BALB/c, C3H/He, C58, CBA, DBA/1, DBA/2, NZB, SWR). Molecular genetic analyses suggest that the Igh-1 [b] allele, which encodes IgG2a [b], is derived from a locus found in several wild mouse subspecies, but not domestic mice, which encodes the IgG2c isotype.

    BD Pharmingen™ Biotin Mouse Anti-Mouse IgG2a [b] - Biotin - Clone 5.7 - Isotype Mouse IgG3, κ - Reactivity Ms - 0.5 mg

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    免疫原

    Not Reported
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Aqueous buffered solution containing protein stabilizer and ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
  • Martin, Silva, Lew: "The Igh-1 sequence of the non-obese diabetic (NOD) mouse assigns it to the IgG2c isotype." in: Immunogenetics, Vol. 46, Issue 2, pp. 167-8, (1997) (PubMed).

    Morgado, Cam, Gris-Liebe, Cazenave, Jouvin-Marche: "Further evidence that BALB/c and C57BL/6 gamma 2a genes originate from two distinct isotypes." in: The EMBO journal, Vol. 8, Issue 11, pp. 3245-51, (1989) (PubMed).

    Huang, Parsons, Oi, Huang, Herzenberg: "Genetic characterization of mouse immunoglobulin allotypic determinants (allotopes) defined by monoclonal antibodies." in: Immunogenetics, Vol. 18, Issue 4, pp. 311-21, (1983) (PubMed).

    Parsons, Oi, Huang, Herzenberg: "Structural characterization of mouse immunoglobulin allotypic determinants (allotopes) defined by monoclonal antibodies." in: Immunogenetics, Vol. 18, Issue 4, pp. 323-34, (1983) (PubMed).

  • 抗原

    IgG2ab (IgG2ab, Subclass Specific)

    别名

    IgG2a [b]
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