小鼠 anti-小鼠 IgG2ab, Subclass Specific Antibody (Biotin)
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Quick Overview for 小鼠 anti-小鼠 IgG2ab, Subclass Specific Antibody (Biotin) (ABIN2689675)
抗原
克隆类型
标记
应用范围
克隆位点
亚型
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适用
- 小鼠
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宿主
- 小鼠
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产品特性
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This antibody reacts specifically with mouse IgG2a of Igh-C [b] haplotype (e.g., C57BL/6, C57BL/10, NOD, SJL). It has been reported not to react with IgG2a of the a, c, d, e, f, g, h, j, n, o, or p haplotypes (e.g., A, AKR, BALB/c, C3H/He, C58, CBA, DBA/1, DBA/2, NZB, SWR). Molecular genetic analyses suggest that the Igh-1 [b] allele, which encodes IgG2a [b], is derived from a locus found in several wild mouse subspecies, but not domestic mice, which encodes the IgG2c isotype.
BD Pharmingen™ Biotin Mouse Anti-Mouse IgG2a [b] - Biotin - Clone 5.7 - Isotype Mouse IgG3, κ - Reactivity Ms - 0.5 mg -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Not Reported
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Aqueous buffered solution containing protein stabilizer and ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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: "The Igh-1 sequence of the non-obese diabetic (NOD) mouse assigns it to the IgG2c isotype." in: Immunogenetics, Vol. 46, Issue 2, pp. 167-8, (1997) (PubMed).
: "Further evidence that BALB/c and C57BL/6 gamma 2a genes originate from two distinct isotypes." in: The EMBO journal, Vol. 8, Issue 11, pp. 3245-51, (1989) (PubMed).
: "Genetic characterization of mouse immunoglobulin allotypic determinants (allotopes) defined by monoclonal antibodies." in: Immunogenetics, Vol. 18, Issue 4, pp. 311-21, (1983) (PubMed).
: "Structural characterization of mouse immunoglobulin allotypic determinants (allotopes) defined by monoclonal antibodies." in: Immunogenetics, Vol. 18, Issue 4, pp. 323-34, (1983) (PubMed).
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: "The Igh-1 sequence of the non-obese diabetic (NOD) mouse assigns it to the IgG2c isotype." in: Immunogenetics, Vol. 46, Issue 2, pp. 167-8, (1997) (PubMed).
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- IgG2ab (IgG2ab, Subclass Specific)
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别名
- IgG2a [b]
抗原
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