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SETD7 蛋白

(SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.

8 results

custom-made SETD7 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7564766
 
custom-made SETD7 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7555491
 
SETD7 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7504524
 
SETD7 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant SDS, WB, ELISA
产品编号 ABIN7579445
 
custom-made SETD7 宿主: 小鼠 宿主: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA
产品编号 ABIN3136750
 
custom-made SETD7 宿主: 人 宿主: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA
产品编号 ABIN3095428
 
SETD7 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2731875
 
SETD7 宿主: Xenopus tropicalis 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN1631635
 
  • 类型 Protein
    • Protein
  • 应用范围
    • ELISA
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • Antibody Production (AbP)
    • Standard (STD)
  • 适用
    • Human
    • Mouse
    • Xenopus tropicalis
  • 图像
  • Carrier free only
  • 抗体来源
    • HEK-293 Cells
    • Cell-free protein synthesis (CFPS)
    • Escherichia coli (E. coli)
    • Yeast
  • 抗原表位
    • AA 1-366
  • 标记
    • His tag
    • Strep Tag
    • Myc-DYKDDDDK Tag
  • 蛋白类型
    • Recombinant
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • custom-made
  • Supplier
    • antibodies-online
    • CUSABIO
    • OriGene

Aliases for SETD7 蛋白

SET domain containing lysine methyltransferase 7 (SETD7) 蛋白
SET domain containing (lysine methyltransferase) 7 (setd7) 蛋白
SET domain containing (lysine methyltransferase) 7 (Setd7) 蛋白
1600028F23Rik 蛋白
H3K4MT 蛋白
KMT7 蛋白
mKIAA1717 蛋白
SET7 蛋白
set7 蛋白
Set7 蛋白
SET7/9 蛋白
Set7/9 蛋白
SET9 蛋白
zgc:92330 蛋白
zgc:101860 蛋白
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