(serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 1 (SERPINB1))
The protein encoded by this gene is a member of the serpin family of proteinase inhibitors. Members of this family maintain homeostasis by neutralizing overexpressed proteinase activity through their function as suicide substrates. This protein inhibits the neutrophil-derived proteinases neutrophil elastase, cathepsin G, and proteinase-3 and thus protects tissues from damage at inflammatory sites. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012].
Gallardo, Barrio, Fernandez, Paradela, Arenas, Toldos, Ayala, Albizua, Jimenez, Redondo, Garcia-Martin, Gilsanz, Albar, Martinez-Lopez: "Proteomic analysis reveals heat shock protein 70 has a key role in polycythemia Vera." in: Molecular cancer, Vol. 12, pp. 142, (2013) (PubMed).
Aliases for SERPINB1 抗体
serpin peptidase inhibitor, clade B (ovalbumin), member 1 (SERPINB1) 抗体 serpin family B member 1 (SERPINB1) 抗体 serpin peptidase inhibitor, clade B (ovalbumin), member 1 (serpinb1) 抗体 serpin family B member 1 L homeolog (serpinb1.L) 抗体 EI 抗体 ELANH2 抗体 elanh2 抗体 LEI 抗体 lei 抗体 M/NEI 抗体 m/nei 抗体 MNEI 抗体 mnei 抗体 PI-2 抗体 PI2 抗体 pi2 抗体 si:dkey-177p2.11 抗体 si:dkey-177p2.12 抗体 zgc:91981 抗体