(serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4 (SERPINA4))
Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.
Biswas, Maihofer, Mir, Rao, Zhang, Khandrika, Mahata, Friese, Hightower, Mahata, Baker, Nievergelt, Vaingankar, OConnor: "Polymorphisms at the F12 and KLKB1 loci have significant trait association with activation of the renin-angiotensin system." in: BMC medical genetics, Vol. 17, pp. 21, (2016) (PubMed).
Aliases for SERPINA4 抗体
kallikrein 1 (KLK1) 抗体 serpin family A member 4 (SERPINA4) 抗体 serpin family A member 4 (Serpina4) 抗体 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 (SPIA4) 抗体 serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1 (Serpina4-ps1) 抗体 DKFZp469E1737 抗体 hK1 抗体 KAL 抗体 kallistatin 抗体 KALps 抗体 Klk6 抗体 KLKR 抗体 KLST 抗体 Klst 抗体 KST 抗体 PI-4 抗体 PI4 抗体 SERPINA4 抗体