SEMA4D/CD100 ELISA试剂盒
(Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))
Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system\; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA (By similarity).
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Latest Publications for our SEMA4D/CD100 ELISA试剂盒
: "A high-sensitivity enzyme immunoassay for the quantification of soluble human semaphorin 4D in plasma." in: Analytical biochemistry, Vol. 574, pp. 15-22, (2020) (PubMed).: "Pathological and therapeutic implications of eosinophil-derived semaphorin 4D in eosinophilic chronic rhinosinusitis. ..." in: The Journal of allergy and clinical immunology, Vol. 145, Issue 3, pp. 843-854.e4, (2020) (PubMed).
: "Semaphorin 4D correlates with increased bone resorption, hypercalcemia, and disease stage in newly diagnosed patients with multiple myeloma." in: Blood cancer journal, Vol. 8, Issue 5, pp. 42, (2019) (PubMed).
: "Genome-wide analysis identifies an african-specific variant in SEMA4D associated with body mass index." in: Obesity (Silver Spring, Md.), Vol. 25, Issue 4, pp. 794-800, (2017) (PubMed).
: "Circulating semaphorin-4D and plexin-B1 levels in postmenopausal women with low bone mass: the 3-month effect of zoledronic acid, denosumab or teriparatide treatment." in: Expert opinion on therapeutic targets, pp. 1-8, (2014) (PubMed).
Aliases for SEMA4D/CD100 ELISA试剂盒
semaphorin 4D (Sema4d) ELISA试剂盒semaphorin 4D (SEMA4D) ELISA试剂盒
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D (Sema4d) ELISA试剂盒
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