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Sema4a 蛋白

(Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4A (Sema4a))
This gene encodes a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in numerous functions, including axon guidance, morphogenesis, carcinogenesis, and immunomodulation. The encoded protein is a single-pass type I membrane protein containing an immunoglobulin-like C2-type domain, a PSI domain and a sema domain. It inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF)-mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo. Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Sep 2010].

13 results

Sema4a 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Pubmed 1 reference
产品编号 ABIN1319469
 
Sema4a 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7320641
 
Sema4a 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
产品编号 ABIN1319471
 
Sema4a 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Pubmed 2 references
产品编号 ABIN2181737
 
Sema4a 宿主: 人 宿主: HEK-293 Cells Recombinant > 92 % by SDS-PAGE.
产品编号 ABIN7520489
 
Sema4a 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7597386
 
Sema4a 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN4371022
 
Sema4a 宿主: 小鼠 宿主: CHO Cells Recombinant >98 % (SDS-PAGE)
产品编号 ABIN6253441
 
Sema4a 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 97 % WB, SDS, Imm, PC
产品编号 ABIN7386176
 
Sema4a 宿主: 人 宿主: HEK-293 Cells Recombinant > 96 % as determined by reducing SDS-PAGE. Active
产品编号 ABIN7317489
 
Sema4a 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE. Active
产品编号 ABIN7317490
 
Sema4a 宿主: 小鼠 宿主: CHO Cells Recombinant >95 % (SDS-PAGE)
产品编号 ABIN7566362
 
Sema4a 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2731626
 
  • 类型 Protein
    • Protein
  • 应用范围
    • Western Blotting (WB)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • ELISA
    • Antibody Production (AbP)
    • Immunogen (Imm)
    • Positive Control (PC)
    • SDS-PAGE (SDS)
    • Standard (STD)
  • 适用
    • Human
    • Mouse
  • 论文引用
  • 图像
  • Carrier free only
  • 抗体来源
    • HEK-293 Cells
    • CHO Cells
    • Human Cells
    • Wheat germ
    • Escherichia coli (E. coli)
  • 抗原表位
    • AA 1-676
    • AA 33-683
    • AA 1-761
    • AA 33-132
    • AA 33-682
  • 标记
    • His tag
    • Fc Tag
    • GST tag
    • Fc Tag,His tag
    • Myc-DYKDDDDK Tag
  • 蛋白类型
    • Recombinant
  • Format
    • Lyophilized
  • 生物活性
    • Biologically Active
  • Supplier
    • antibodies-online
    • ACROBiosystems
    • OriGene

Latest Publications for our Sema4a 蛋白

Chiou, Lucassen, Sather, Kallianpur, Connor: "Semaphorin4A and H-ferritin utilize Tim-1 on human oligodendrocytes: A novel neuro-immune axis." in: Glia, Vol. 66, Issue 7, pp. 1317-1330, (2018) (PubMed).

Peng, Gao, Chong, Liu, Zhang: "Semaphorin 4A enhances lung fibrosis through activation of Akt via PlexinD1 receptor." in: Journal of biosciences, Vol. 40, Issue 5, pp. 855-62, (2015) (PubMed).

Mogie, Shanks, Nkyimbeng-Takwi, Smith, Davila, Lipsky, DeTolla, Keegan, Chapoval: "Neuroimmune semaphorin 4A as a drug and drug target for asthma." in: International immunopharmacology, Vol. 17, Issue 3, pp. 568-75, (2013) (PubMed).

Aliases for Sema4a 蛋白

semaphorin 4A (SEMA4A) 蛋白
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A (sema4a) 蛋白
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A (Sema4a) 蛋白
semaphorin 4A (Sema4a) 蛋白
AI132332 蛋白
CORD10 蛋白
RP35 蛋白
SEMA4A 蛋白
SEMAB 蛋白
Semab 蛋白
SEMB 蛋白
SemB 蛋白
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