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Secreted Epidermal Growth Factor 蛋白

(Secreted Epidermal Growth Factor (C11R))
Vaccinia growth factor stimulates cellular proliferation (hyperplasia) around infected cells. This effect is beneficial for virus replication in vivo, because poxviruses replicate possibly better in proliferating cells than in quiescent cells. Acts by binding host EGFR, inducing its dimerization, autophosphorylation and leading to activation of several cellular pathways regulating cell proliferation or cell survival. The activation by host EFGR of mitogen activated protein kinases (MAPK) and extracellular- signal regulated kinases (ERK) are essential for the positive effect of vaccinia growth factor on poxvirus virulence in vivo.

1 results :

C11R 宿主: Vaccinia Virus (VACV) 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN1593871
 
  • 类型 Protein
    • Protein
  • 应用范围
    • ELISA
  • 适用
    • Vaccinia Virus (VACV)
  • Carrier free only
  • 抗体来源
    • Yeast
  • 抗原表位
    • AA 19-100
  • 标记
    • His tag
  • 蛋白类型
    • Recombinant
  • Format
    • Lyophilized
  • Supplier
    • CUSABIO

Aliases for Secreted Epidermal Growth Factor 蛋白

temporal expression: early (C11R) 蛋白
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