The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23\\/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. This gene product is implicated in the shaping of the vesicle, and also in cargo selection and concentration. [provided by RefSeq, Jul 2008].
Chanoux, Robay, Shubin, Kebler, Suaud, Rubenstein: "Hsp70 promotes epithelial sodium channel functional expression by increasing its association with coat complex II and its exit from endoplasmic reticulum." in: The Journal of biological chemistry, Vol. 287, Issue 23, pp. 19255-65, (2012) (PubMed).
Slavin, García, Monetta, Martinez, Romero, Alvarez: "Role of Rab1b in COPII dynamics and function." in: European journal of cell biology, Vol. 90, Issue 4, pp. 301-11, (2011) (PubMed).
Sharpe, Luu, Brown: "Akt phosphorylates Sec24: new clues into the regulation of ER-to-Golgi trafficking." in: Traffic (Copenhagen, Denmark), Vol. 12, Issue 1, pp. 19-27, (2010) (PubMed).
Lee, Ajay, Yook, Kim, Hong, Kim, Dhanasekaran, Chinnaiyan, Athey: "New class of microRNA targets containing simultaneous 5'-UTR and 3'-UTR interaction sites." in: Genome research, Vol. 19, Issue 7, pp. 1175-83, (2009) (PubMed).
Aliases for SEC24D 抗体
SEC24 homolog D, COPII coat complex component (SEC24D) 抗体 Sec24 related gene family, member D (S. cerevisiae) (Sec24d) 抗体 SEC24 homolog D, COPII coat complex component (Sec24d) 抗体 SEC24 homolog D, COPII coat complex component S homeolog (sec24d.S) 抗体 2310020L09Rik 抗体 Gm1349 抗体 sec24d 抗体