The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The product of this gene may play a role in shaping the vesicle, as well as in cargo selection and concentration. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008].
Kovalchuk, Samluk, Juraszek, Jurkiewicz-Trząska, Sucic, Freissmuth, Nałęcz: "Trafficking of the amino acid transporter B0,+ (SLC6A14) to the plasma membrane involves an exclusive interaction with SEC24C for its exit from the endoplasmic reticulum." in: Biochimica et biophysica acta. Molecular cell research, Vol. 1866, Issue 2, pp. 252-263, (2019) (PubMed).
Bachmann, Burté, Pramana, Conte, Brown, Orimadegun, Ajetunmobi, Afolabi, Akinkunmi, Omokhodion, Akinbami, Shokunbi, Kampf, Pawitan, Uhlén, Sodeinde, Schwenk, Wahlgren, Fernandez-Reyes, Nilsson: "Affinity proteomics reveals elevated muscle proteins in plasma of children with cerebral malaria." in: PLoS pathogens, Vol. 10, Issue 4, pp. e1004038, (2014) (PubMed).
Aliases for SEC24C 抗体
Sec24 related gene family, member C (S. cerevisiae) (Sec24c) 抗体 SEC24 homolog C, COPII coat complex component (Sec24c) 抗体 SEC24 homolog C, COPII coat complex component (SEC24C) 抗体 2610204K03Rik 抗体 mKIAA0079 抗体