The protein encoded by this gene contains two class II PDZ domains. PDZ domains facilitate protein-protein interactions by binding to the cytoplasmic C-terminus of transmembrane proteins, and PDZ-containing proteins mediate cell signaling and the organization of protein complexes. The encoded protein binds to phosphatidylinositol 4, 5-bisphosphate (PIP2) and plays a role in nuclear PIP2 organization and cell division. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Read-through transcription also exists between this gene and the upstream FKBP1A (FK506 binding protein 1A, 12kDa) gene, as represented in GeneID:100528031. [provided by RefSeq, Sep 2011].
Koroll, Rathjen, Volkmer: "The neural cell recognition molecule neurofascin interacts with syntenin-1 but not with syntenin-2, both of which reveal self-associating activity." in: The Journal of biological chemistry, Vol. 276, Issue 14, pp. 10646-54, (2001) (PubMed).
Aliases for SDCBP2 抗体
syndecan binding protein 2 (SDCBP2) 抗体 syndecan binding protein (syntenin) 2 (Sdcbp2) 抗体 syndecan binding protein 2 (Sdcbp2) 抗体 suppression of tumorigenicity 2 (ST2) 抗体 SITAC 抗体 SITAC18 抗体 ST-2 抗体