This gene encodes a protein with a kinase domain and four HEAT repeats. The encoded protein interacts with the C-terminal domain of ezrin, an ERM protein, and may play a role in cell adhesion and migration. Alternative splicing results in multiple transcript variants encoding multiple isoforms. [provided by RefSeq, Jun 2012].
Sullivan, Uff, Isacke, Thorne: "PACE-1, a novel protein that interacts with the C-terminal domain of ezrin." in: Experimental cell research, Vol. 284, Issue 2, pp. 224-38, (2003) (PubMed).