The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is widely expressed in various types of tissues with a high expression level in thyroid gland. In smooth muscle cells, this protein co-expresses with other family members in the nucleus and in stress fibers, suggesting diverse functions in signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
Dinets, Pernemalm, Kjellin, Sviatoha, Sofiadis, Juhlin, Zedenius, Larsson, Lehtiö, Höög: "Differential protein expression profiles of cyst fluid from papillary thyroid carcinoma and benign thyroid lesions." in: PLoS ONE, Vol. 10, Issue 5, pp. e0126472, (2015) (PubMed).
Azimi, Pernemalm, Frostvik Stolt, Hansson, Lehtiö, Egyházi Brage, Hertzman Johansson: "Proteomics analysis of melanoma metastases: association between S100A13 expression and chemotherapy resistance." in: British journal of cancer, Vol. 110, Issue 10, pp. 2489-95, (2014) (PubMed).
Aliases for S100A13 抗体
S100 calcium binding protein A13 (S100A13) 抗体 S100 calcium binding protein A13 (S100a13) 抗体 protein S100-A13 (LOC100345691) 抗体 S100A1 抗体 S100A13 抗体