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抗Human VEGFC 抗体:
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抗Rat (Rattus) VEGFC 抗体:
Human Polyclonal VEGFC Primary Antibody for IHC (fro), IHC (p) - ABIN258871
Zampell, Yan, Avraham, Daluvoy, Weitman, Mehrara: HIF-1α coordinates lymphangiogenesis during wound healing and in response to inflammation. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012
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Human Polyclonal VEGFC Primary Antibody for IP, ELISA - ABIN541859
Krishnan, Kirkin, Steffen, Hegen, Weih, Tomarev, Wilting, Sleeman: Differential in vivo and in vitro expression of vascular endothelial growth factor (VEGF)-C and VEGF-D in tumors and its relationship to lymphatic metastasis in immunocompetent rats. in Cancer research 2003
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Human Polyclonal VEGFC Primary Antibody for IF (p), IHC (p) - ABIN731723
Zhuo, Jia, Song, Lu, Ding, Wang, Song, Fu, Luo: The CXCL12-CXCR4 chemokine pathway: a novel axis regulates lymphangiogenesis. in Clinical cancer research : an official journal of the American Association for Cancer Research 2012
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Human Polyclonal VEGFC Primary Antibody for FACS, IHC (p) - ABIN650694
Yan, Zhu, Yu, Ji, Zhang, Ji, Yan, Chen, Liu, Yin, Lin: Expression of vascular endothelial growth factor C and chemokine receptor CCR7 in gastric carcinoma and their values in predicting lymph node metastasis. in World journal of gastroenterology : WJG 2004
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Human Monoclonal VEGFC Primary Antibody for ICC, IHC (fro) - ABIN438679
Moussai, Mitsui, Pettersen, Pierson, Shah, Suárez-Fariñas, Cardinale, Bluth, Krueger, Carucci: The human cutaneous squamous cell carcinoma microenvironment is characterized by increased lymphatic density and enhanced expression of macrophage-derived VEGF-C. in The Journal of investigative dermatology 2010
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Rat (Rattus) Polyclonal VEGFC Primary Antibody for IP, ELISA - ABIN1589911
Maertens, Erpicum, Detry, Blacher, Lenoir, Carnet, Péqueux, Cataldo, Lecomte, Paupert, Noel: Bone marrow-derived mesenchymal stem cells drive lymphangiogenesis. in PLoS ONE 2014
These findings thus underscore a role for posterior cardinal (显示 CARD8 抗体) vein and VegfC in patterning the head kidney prior to organ assembly and function.
Vegfc acts through ERK (显示 MAPK1 抗体) to induce sprouting and differentiation of trunk lymphatic progenitors.
data not only reveal a non-canonical function of Mt2 (显示 MT2 抗体) in angiogenesis, but also propose Mt2 (显示 MT2 抗体) as a novel regulator of vegfc expression.
Vegfc signaling increases mafba (显示 MAFB 抗体) expression to control downstream transcription
Vegfc is dispensable for facial lymphatic sprouting but not for the complete development of the facial lymphatic network.
In the embryo, phenotypes driven by increased Vegfc are suppressed in the absence of Ccbe1 (显示 CCBE1 抗体), and Vegfc-driven sprouting is enhanced by local Ccbe1 (显示 CCBE1 抗体) overexpression. Moreover, Vegfc- and Vegfr3 (显示 FLT4 抗体)-dependent Erk (显示 MAPK1 抗体) signaling is impaired in the absence of Ccbe1 (显示 CCBE1 抗体).
Vegfc has an essential role in lymphangiogenesis [review]
The parallel growth of motoneuron axons with the dorsal aorta depends on Vegfc/Vegfr3 (显示 FLT4 抗体) signaling in zebrafish.
Vegfc acts in two distinct modes during development: as a paracrine factor secreted from arteries to guide closely associated lymphatic vasculature and as an autocrine factor to drive migratory persistence during angiogenesis.
Rspo1-Wnt-VegfC-Vegfr3 signaling plays a crucial role as an endothelial-autonomous permissive cue for developmental angiogenesis.
VEGF-C and VEGF (显示 VEGFA 抗体)-C156S genes have roles in the pro-lymphangiogenic growth factor therapy of lymphedema
Transcription of the vascular endothelial growth factor C gene (VEGF-C) and translation of the corresponding protein were significantly up-regulated in swine umbilical vein endothelial cells with classical swine fever virus acute infection.
No difference in bioactivity was detected between porcine relaxin-1 (显示 RLN1 抗体) and recombinant human relaxin-2 (显示 RLN1 抗体) in either mice or rats.
During progressive ischemia, functional and metabolic benefits of intramyocardial VEGF-C gene transfer were apparent. VEGF-C-induced collateral formation occurred at the site of gene transfer
SPARC (显示 SPARC 抗体) expression was inversely associated with the degree of malignancy and it had a negative correlation with VEGF-C and VEGF-D (显示 Figf 抗体) expression. Results suggest SPARC (显示 SPARC 抗体) might function as a tumor suppressor inhibiting angiogenesis and lymphangiogenesis in ovarian cancer by reducing the expression of VEGF-C and VEGF-D (显示 Figf 抗体).
VEGF-A/VEGF (显示 VEGFA 抗体)-C analysis showed higher positivity in metastatic nodes and higher positivity in the surrounding negative nodes from positive cases in comparison with nonmetastatic patients.
this study shows that decidual NK cells facilitate the interaction between trophoblastic and endothelial cells via VEGF-C and HGF (显示 HGF 抗体)
Lymphangiogenesis during tubulointerstitial fib (显示 CTGF 抗体)rosis to be associated with increased expression of CTGF and VEGF-C in human obstructed nephropathy as well as in diabetic kidney disease. vitro, CTGF induced VEGF-C production in HK-2 cells, while CTGF siRNA suppressed transforming growth factor beta1-induced VEGF-C upregulation.
Smad4 (显示 SMAD4 抗体) expression negatively correlated with VEGF-A (显示 VEGFA 抗体) and VEGF-C in colon cancer
study is the first to describe the mechanism of leptin (显示 LEP 抗体)-promoted lymphangiogenesis by upregulating VEGF-C expression in chondrosarcomas.
Retroperitoneal tumour progression in EOC patients is associated with high VEGF-C expression.
Mechanistic investigations indicated that BDNF (显示 BDNF 抗体) facilitated VEGF-C-dependent lymphangiogenesis through the MEK (显示 MAP2K1 抗体)/ERK (显示 EPHB2 抗体)/mTOR (显示 FRAP1 抗体) signaling pathway.
no difference in the levels of VEGF-A (显示 VEGFA 抗体), VEGF-C, and VEGF-D (显示 Figf 抗体) in pre-eclampsia compared to normotensive pregnant women stratified by HIV status
Results has shown that VEGF-C was highly expressed in non-small cell lung cancer (NSCLC) tissues and metastatic lymph nodes. VEGF-C expression levels was significantly correlated with lymph node metastasis in NSCLC. Along with CXCR4 (显示 CXCR4 抗体), VEGF-C might synergically promote lymphatic metastasis in lung cancer and might be a clinical predictor of lymph node metastasis in NSCLC patients.
As shown in mouse model of kidney fibrosis CTGF (显示 CTGF 抗体) is significantly involved in fibrosis-associated renal lymphangiogenesis through regulation of, and direct interaction with, VEGF-C.
Fluid shear stress regulates vascular remodeling via VEGFR-3 (显示 FLT4 抗体) activation, independently of its ligand, VEGF-C, in the uterus during pregnancy.
A novel heparin conjugate (LHbisD4) is shown to prevent lymphangiogenesis by blocking the vascular endothelial growth factor C (VEGF-C) induced signaling pathway.
lymphangiogenesis is regulated by two distinct proteolytic mechanisms of ligand activation: one in which VEGFC activation by ADAMTS3 (显示 Adamts2 抗体) and CCBE1 (显示 CCBE1 抗体) spatially and temporally patterns developing lymphatics, and one in which VEGFD (显示 Figf 抗体) activation by a distinct proteolytic mechanism may be stimulated during inflammatory lymphatic growth
These results reveal an unexpected role for VEGF-C, a major lymphangiogenic growth factor, in the transition to fetal liver erythropoiesis.
Results suggest that interleukin-6 (IL-6 (显示 IL6 抗体)) increases VEGF-C induction and lymphangiogenesis may involve, at least in part, Src (显示 SRC 抗体)-FAK (显示 PTK2 抗体)-STAT3 (显示 STAT3 抗体) cascade in lymphatic endothelial cells (LECs).
Data show that heparanase-1 (HPA-1 (显示 HPSE 抗体)) induced shedding of heparan sulfate chain from syndecan-1 (SDC-1 (显示 SDC1 抗体)) facilitated the release of vascular endothelial growth factor C (VEGF-C) from SDC-1 (显示 SDC1 抗体)/VEGF-C complex into the medium of hepatocarcinoma cell.
Data show that in the MCF-7 breast cancer cell line, only MT1X (显示 MT1X 抗体) metallothioneins (MTs (显示 NEU2 抗体)) positively correlated with vascular endothelial growth factor C (VEGFC).
The findings in this study strongly suggest the following: i) that VEGF-C promotes the proliferative activity and migratory ability of mesenchymal stem cell ; and ii) VEGF-C and Tgfb (显示 TGFB1 抗体) reciprocally regulate mesenchymal stem cell commitment to differentiation into lymphatic endothelial or osteoblastic phenotypes, respectively.
The authors show that VEGF-C is necessary for perinatal lymphangiogenesis, but required for adult lymphatic vessel maintenance only in the intestine.
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.
vascular endothelial growth factor C
, vascular endothelial growth factor c
, FLT4 ligand DHM
, vascular endothelial growth factor-related protein
, flt4 ligand
, vascular endothelial growth factor C isoform 129
, vascular endothelial growth factor C isoform 184