蛋白简介

The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations\; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.

Alternative names and synonyms associated with TEK

• TEK receptor tyrosine kinase (TEK) 抗体
• angiopoietin-1 receptor (LOC100408334) 抗体
• TEK receptor tyrosine kinase (tek) 抗体
• TEK receptor tyrosine kinase (Tek) 抗体
• TEK tyrosine kinase, endothelial (tek) 抗体

• AA517024 抗体
• CD202B 抗体
• DKFZp469E064 抗体
• Hyk 抗体
• TEK 抗体
• 显示所有的同义词和别名
• Tie-2 抗体
• tie2 抗体
• VMCM 抗体
• VMCM1 抗体

Protein level used designations for TEK

growth factor receptor Tie2/Tek , TEK tyrosine kinase, endothelial (venous malformations, multiple cutaneous and mucosal) , Angiopoietin-1 receptor , TEK tyrosine kinase, endothelial , angiopoietin-1 receptor-like , STK1 , angiopoietin-1 receptor , endothelial tyrosine kinase , mTIE2 , p140 TEK , tunica interna endothelial cell kinase , tyrosine kinase with Ig and EGF homology domains-2 , tyrosine-protein kinase receptor TEK , tyrosine-protein kinase receptor TIE-2 , hTIE2 , soluble TIE2 variant 1 , soluble TIE2 variant 2 , protein-tyrosine kinase Tie2 , endothelial-specific receptor tyrosine kinase , tyrosine kinases that contain immunoglobulin-like loops and epidermal growth factor-similar domains 2 , endothelium-specific receptor tyrosine kinase 2 , tyrosine-protein kinase receptor Tie-2