anti-Neurotrophin 3 (NTF3) 抗体产品概述

Human Neurotrophin 3 (NTF3) interaction partners

1. brain-derived neurotrophic factor (BDNF (显示 BDNF 抗体)) and neurotrophin 3 (NT3) levels in post-mortem brain tissue from patients with depression compared to healthy individuals - a proof of concept study

2. NT-3 has been shown to be both an osteogenic and angiogenic factor (显示 VEGFA 抗体), and can also enhance expression of the key osteogenic factor, BMP-2 (显示 BMP2 抗体), as well as the major angiogenic factor (显示 VEGFA 抗体), VEGF (显示 VEGFA 抗体), to promote bone formation, vascularization, and bone healing

3. High expression of NT-3 is associated with glioblastoma.

4. Meta-analysis found the levels of both NT-3 and NT-4/5 (显示 NTF4 抗体) were significantly increased in bipolar disorder patients. Through subgroup analysis, this increase persisted only in patients in depressed state, but not in manic or euthymic state. In addition, we found the differences in NT-3 and NT-4/5 (显示 NTF4 抗体) were significantly associated with the duration of illness, but not by the mean age or female proportion.

5. NT3 upregulates cellular proliferation, extracellular matrix protein production, and collagen deposition in human aortic valve interstitial cells through the Trk (显示 NTRK1 抗体)-Akt (显示 AKT1 抗体)-cyclin D1 (显示 CCND1 抗体) cascade.

6. The analysis of covariance (ANCOVA) indicated that the mean serum GDNF and NTF3 levels of ADHD patients were significantly higher than that of controls. However, serum BDNF (显示 BDNF 抗体) and NGF (显示 NGFB 抗体) levels did not show any significant differences between groups. These results suggest that elevated serum GDNF and NTF3 levels may be related to ADHD in children.

7. All patients had serum neurotrophin (显示 BDNF 抗体) (NT-3, BDNF (显示 BDNF 抗体), NGF (显示 NGFB 抗体)) concentrations determined.

8. There were no differences in neurotrophin (显示 BDNF 抗体) levels between patients with schizophrenia and controls. We found lower BDNF (显示 BDNF 抗体) and higher NT-3 serum levels in depressed patients with schizophrenia.

9. The results suggest a gene dose-association between the A allele of rs6332 and the onset of AD in varepsilon4 non-carriers and the NTF-3 rs6489630 polymorphism being a relevant risk factor for AD in patients lacking the ApoE (显示 APOE 抗体)-varepsilon4 allele in this Chinese sample.

10. Survival, differentiation, and neuroprotective mechanisms of human stem cells complexed with neurotrophin-3-releasing pharmacologically active microcarriers in an ex vivo model of Parkinson's disease.

Zebrafish Neurotrophin 3 (NTF3) interaction partners

1. By immunohistochemistry, the localization of Neurotrophinss has been observed mainly in Purkinje cells; TrkA (显示 NTRK1 抗体) and TrkB (显示 NTRK2 抗体)-receptors in cells and fibers of granular and molecular layers. TrkC (显示 NTRK3 抗体) was faintly detected

2. Deletion of a kinesin I motor unmasks a mechanism of homeostatic axon-branching control by neurotrophin-3.

Mouse (Murine) Neurotrophin 3 (NTF3) interaction partners

1. that the NT3-TrkA (显示 NTRK1 抗体) complex uses Ras/MAPK (显示 MAPK1 抗体) and/or PI3K-AKT (显示 AKT1 抗体) signaling to induce axon growth and inhibit axon branching along intermediate targets

2. Here the authors demonstrate a novel function for p75(NTR (显示 NGFR 抗体)) in regulating proper cell cycle exit of neuronal progenitors in the developing rat and mouse external granule layer, which is stimulated by proneurotrophin-3. In the absence of p75(NTR (显示 NGFR 抗体)), cerebellar granule cell progenitors continue to proliferate beyond their normal period, resulting in a larger cerebellum that persists into adulthood, with consequent motor defici

3. NT-3-transduced bone marrow- derived neural stem cells differentiated into a greater number of cholinergic neurons.

4. Ntf3, but not Bdnf (显示 BDNF 抗体), expression by postnatal supporting cells regulates cochlear function.

5. Study shows that dissociated cochlear nucleus neurons can be stimulated by neurotrophic factors BDNF (显示 BDNF 抗体), NT-3, and FGF2 (显示 FGF2 抗体)

6. Data show that acteoside can up-regulate the expression of brain neurotrophin-3 (NT-3) in D-galactose combined with aluminum trichloride treated mice.

7. CAPS2 (显示 CADPS2 抗体) plays an important role in subcellular locality (axonal vs. somato (显示 SSTR5 抗体)-dendritic) of enhanced BDNF (显示 BDNF 抗体) and NT-3 release, which is indispensable for proper development of postnatal cerebellum.

8. Uptake of NT-3 from irrigating vasculature and cerebrospinal fluid induces the rapid phosphorylation of endothelial nitric oxide

9. Loss of Ntf3, by contrast, causes an increase in layer VI neurons but does not rescue the Sip1 (显示 ZEB2 抗体) mutant phenotype, implying that other parallel pathways also control the timing of progenitor cell fate switch.

10. it was PDGF, NT-3 and IGF-2 in combination that conducted the transdifferentiation