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Human FLT1 ELISA Kit for Sandwich ELISA - ABIN414833
Sun, Huang, Phillips, Luo, Zhu, Shi, Li: Growth differentiation factor 15 and coronary collateral formation. in Clinical cardiology 2010
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Human FLT1 ELISA Kit for Sandwich ELISA - ABIN411372
Du, Liu, Zhao, Wu, Gong, Zhou, Xu, Li, Shi, Qiao: Effects of maternal serum on permeability of glomerular endothelial cell membrane. in Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2011
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This is the first report demonstrating the spatiotemporal expression patterns of Flk1 (显示 KDR ELISA试剂盒) and Flt1 in the coronary vascular system during development and after MI; thus, this study suggests that these factors have distinct and important functions in coronary angiogenesis.
sFlt-1 overexpression in Padi4 (显示 PADI4 ELISA试剂盒)(-/-) mice resulted in dramatically lower inflammatory and thrombotic response, which was accompanied by significant reduction in pregnancy losses. Inhibition of NETosis may serve as a novel target in disorders of impaired placentation.
endothelial dysfunction due to high circulating sFLT1 may be the primary event leading to enhanced vasoconstrictor sensitivity that is characteristic of preeclampsia
Flt1 has a role in blood vessel anastomosis during angiogenesis
First-in-class selective PET tracers for imaging VEGFR-1 and VEGFR-2 (显示 KDR ELISA试剂盒) were constructed and successfully validated in an orthotopic murine tumor model.
these results suggest that VEGFR1 signaling plays a role in regulating the balance between macrophage phenotypes in streptozotocin -induced diabetic wounds, prevents impaired diabetic wound healing, and promotes angiogenesis/lymphangiogenesis.
These data therefore support a tightly controlled, paracrine signaling mechanism of VEGF-B (显示 VEGFB ELISA试剂盒) to VEGFR1.
Flt1/VEGF-A (显示 VEGFA ELISA试剂盒) signalling has stage-specific effects on vascular morphogenesis.
IL-35 treatment reduced collagen-induced arthritis via inhibiting vascular endothelial growth factor and its receptors
the VEGFR-1 tyrosine kinase (显示 TYRO3 ELISA试剂盒) signaling has an effect on angiogenesis.
Altered antiangiogenic state because of altered circulating sFlt1 leads to Preeclampsia, ratio of sFlt1/PlGF (显示 PGF ELISA试剂盒) correlates with Preeclampsia phenotypes.
Gestation-adjusted sEng, sFlt-1 and PlGF (显示 PGF ELISA试剂盒) levels were 11%, 36%, and 30%, respectively, lower in women who later suffered miscarriage compared with unaffected pregnancies
the optimal discrimination cut-off for each cytokine: sVEGFR-1 (2124.5pg/mL), IL-6 (显示 IL6 ELISA试剂盒) (40.2pg/mL), VEGF-A (显示 VEGFA ELISA试剂盒) (1060.1pg/mL), Angiopoeintin-2 (913.7pg/mL), uPA (显示 PRAP1 ELISA试剂盒) (248.1pg/mL), sHER-2/neu (显示 ERBB2 ELISA试剂盒) (5010pg/mL) and PLGF (显示 PGF ELISA试剂盒) (93.4pg/mL). For the very first time, a novel cytokine profile associated with cancer metastasis to the paratracheal lymph nodes were reported.
Results indicate that miR (显示 MLXIP ELISA试剂盒)-507 represented potential therapeutic targets in breast cancer by modulating fms-related tyrosine kinase-1 (Flt-1).
VEGF (显示 VEGFA ELISA试剂盒)-Flt-1 signaling induces osteoclastogenesis in OSCC through two possible ways: 1) VEGF (显示 VEGFA ELISA试剂盒) produced from OSCC cells can directly stimulate the Flt-1 pathway in preosteoclasts to induce migration to future bone resorbing area and differentiation into osteoclasts, and 2) VEGF (显示 VEGFA ELISA试剂盒)-Flt-1 signaling upregulates RANKL (显示 TNFSF11 ELISA试剂盒) expression in OSCC cells, which indirectly leads to osteoclast differentiation
Study demonstrates that placental-specific overexpression of hsFlt-1 alters placental morphology and trophoblast differentiation and interferes with IGF2 and nutrient transporter expression leading to intrauterine growth restriction.
this study found no difference in VEGFR1 expression in infantile hemangiomas from the study and control group
MiRNA199a-3p suppresses tumor growth, migration, invasion and angiogenesis in hepatocellular carcinoma by targeting VEGFA (显示 VEGFA ELISA试剂盒), VEGFR1, VEGFR2 (显示 KDR ELISA试剂盒), HGF (显示 HGF ELISA试剂盒) and MMP2 (显示 MMP2 ELISA试剂盒)
The SNPs rs9554322, rs9582036 and rs9943922 were correlated with age-related macular degeneration (AMD (显示 AMD1 ELISA试剂盒)). Gene variants in VEGFR1 were linked to a pronounced emerging risk for AMD (显示 AMD1 ELISA试剂盒) in a population in northern China.
Leptin (显示 LEP ELISA试剂盒)-induced transphosphorylation of vascular endothelial growth factor receptor (显示 RYK ELISA试剂盒) increases Notch (显示 NOTCH1 ELISA试剂盒) and stimulates endothelial cell angiogenic transformation
There is a possibility that steatosis can be suppressed by the CC genotype in VEGFR1.
These results suggest that non-dominant follicles maintain a greater concentration of the mRNA expression of both membrane and soluble VEGF receptors; but follicular dominance is related to a reduction in the mRNA expression of sVEGFR1 and sVEGFR2.
VEGFR-1 negatively regulates primary bovine retinal pericytes survival, and its blockade protects the blood-brain barrier integrity.
gamma-Secretase and presenilin mediate cleavage and phosphorylation of vascular endothelial growth factor receptor-1
VEGFR1 mRNA expression was lower at estrus and at the early I and early II luteal stages than at the other stages, whereas VEGFR1 protein expression did not change significantly throughout the estrous cycle (P<0.05)
Alterations in the expression of VEGF-A (显示 VEGFA ELISA试剂盒) and bFGF (显示 FGF2 ELISA试剂盒) systems suggest that angiogenic factors are involved in abnormal placental development in cloned gestations, contributing to impaired fetal development and poor survival rates.
inhibition of VEGFR-1 results in decrease in number of capillary connections indicating VEGFR-1 ligands promote branching angiogenesis.
TGF-beta1 (显示 TGFB1 ELISA试剂盒) induction of VEGFR-1 in endothelial cells explains pericyte protection of vessels and the selective vulnerability of neonatal vessels to oxygen(VEGFR-1)
the activation of VEGFR-1 and VEGFR-2 (显示 KDR ELISA试剂盒) heterodimer (VEGFR-1/R-2) is essential for PGI(2 (显示 PTGIR ELISA试剂盒)) synthesis mediated by VEGF-A (显示 VEGFA ELISA试剂盒)(165) and VEGF-A (显示 VEGFA ELISA试剂盒)(121), which cannot be reproduced by the parallel activation of VEGFR-1 and VEGFR-2 (显示 KDR ELISA试剂盒) homodimers with corresponding agonists
PEDF (显示 SERPINF1 ELISA试剂盒) and VEGFR-1 have roles in the negative regulation of angiogenesis
we analyzed the expression and cellular distribution of Flt-1(VEGFR-1) and Flk-1 (KDR/VEGFR-2 (显示 KDR ELISA试剂盒))in newborn piglet brain
data shows that members of the VEGF (显示 VEGFA ELISA试剂盒)-VEGFR (显示 KDR ELISA试剂盒) system are temporally and spatially well localized for playing key roles during umbilical cord formation and its intensive growth observed after day 75 of pregnancy
The VEGFR1 was stably expressed during the whole lifespan of mesonephric glomeruli, and VEGFR1 is important for the maintenance of endothelial fenestrations.
increased placental expression of the VEGF receptor system is associated with increased placental vascular density observed with the advancement of gestation in the pig.
EGFR (显示 EGFR ELISA试剂盒), VEGFR (显示 KDR ELISA试剂盒) and FGFR (显示 FGFR2 ELISA试剂盒) are expressed in porcine oviduct and endometrium during the time of implantation [review]
VEGF ligand-receptor system may play an important role in the development and maintenance of the corpus luteum in pigs.
VEGF (显示 VEGFA ELISA试剂盒)/Flk-1 (显示 KDR ELISA试剂盒)/Flt-1 system is activated during myocardial ischemia reperfusion injury.
Hemodialysis graft placement leads to early increases in wall shear stress, VEGF-A (显示 VEGFA ELISA试剂盒), pro-MMP-9 (显示 MMP9 ELISA试剂盒), MMP-2 (显示 MMP2 ELISA试剂盒), VEGFR-1, VEGFR-2 (显示 KDR ELISA试剂盒), and TIMP-1 (显示 TIMP1 ELISA试剂盒), which may contribute to the development of venous stenosis.
in experimental intervertebral disc degeneration, VEGF receptors were expressed in the damaged disc and paradiscal tissues
we determined that radial glia control this process via the Vegf (显示 VEGFA ELISA试剂盒) decoy receptor sFlt1: sflt1 mutants exhibit the venous over-sprouting observed in radial glia-ablated larvae, and sFlt1 overexpression rescues it. Genetic mosaic analyses show that sFlt1 function in trunk endothelial cells can limit their over-sprouting.
Flt1-tyrosine kinase (TK) activity contributed significantly in endothelial cells survival and vascular development during embryo angiogenesis in zebrafish by engaging PI3K/Akt (显示 AKT1 ELISA试剂盒) pathway.
Elevated Notch (显示 NOTCH1 ELISA试剂盒) signaling downstream of perturbed VEGF (显示 VEGFA ELISA试剂盒) signaling contributes to aberrant flt-1(-/-) blood vessel formation.
Data indicate that the increase in FLT1/sFLT1 protein levels upon miR-10 (显示 LILRB2 ELISA试剂盒) knockdown inhibited the angiogenic behavior of endothelial cells largely by antagonizing vascular endothelial growth factor receptor 2 (显示 KDR ELISA试剂盒) signaling.
This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.
fms-related tyrosine kinase 1
, vascular endothelial growth factor receptor 1
, embryonic receptor kinase 2
, tyrosine-protein kinase receptor FLT
, vascular endothelial growth factor receptor-1
, vascular permeability factor receptor
, fms-like tyrosine kinase 1
, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
, tyrosine-protein kinase FRT
, FMS-like tyrosine kinase 1
, Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
, vascular endothelial growth factor 1
, vascular endothelial growth factor/vascular permeability factor receptor
, ascular endothelial growth factor/vascular permeability factor receptor
, flt-1 type VEGF receptor
, receptor tyrosine kinase Flt1b
, soluble fms-like tyrosine kinase 1