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RPSA/Laminin Receptor 产品

(Ribosomal Protein SA (RPSA))
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured RPSA/Laminin Receptor Categories

RPSA/Laminin Receptor 抗体

High quality antibodies with extensive validation data.

RPSA/Laminin Receptor ELISA试剂盒

Reliable ELISA kits for a wide range of species.

RPSA/Laminin Receptor 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RPSA/Laminin Receptor 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF, FACS, StM
Validations
  • (10)
Cat. No. ABIN6939957
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN6147247
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (4)
Cat. No. ABIN2854873
Quantity 100 μL
Datasheet Datasheet

Recommended RPSA/Laminin Receptor ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959194
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1745001
Quantity 96 tests
Datasheet Datasheet
Reactivity Monkey
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1771016
Quantity 96 tests
Datasheet Datasheet

Recommended RPSA/Laminin Receptor 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1318866
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1318864
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3132971
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our RPSA/Laminin Receptor Products

Umbaugh, Diaz-Quiñones, Neto, Shearer, Figueiredo: "A dock derived compound against laminin receptor (37 LR) exhibits anti-cancer properties in a prostate cancer cell line model." in: Oncotarget, Vol. 9, Issue 5, pp. 5958-5978, (2018) (PubMed).

Wang, Yu, Guan, Liu, Qiao: "67-kDa Laminin receptor contributes to hypoxia-induced migration and invasion of trophoblast-like cells by mediating matrix metalloproteinase-9." in: Clinical and experimental pharmacology & physiology, Vol. 42, Issue 5, pp. 549-58, (2015) (PubMed).

Santamarina, Oliveira, Silva, Carnier, Mennitti, Santana, de Souza, Ribeiro, Oller do Nascimento, Lira, Oyama: "Green Tea Extract Rich in Epigallocatechin-3-Gallate Prevents Fatty Liver by AMPK Activation via LKB1 in Mice Fed a High-Fat Diet." in: PLoS ONE, Vol. 10, Issue 11, pp. e0141227, (2015) (PubMed).

Song, Choi, Cho, Sung, Song, Kim, Bae, Lee, Kim: "Expression of 67-kDa laminin receptor was associated with tumor progression and poor prognosis in epithelial ovarian cancer." in: Gynecologic oncology, Vol. 125, Issue 2, pp. 427-32, (2012) (PubMed).

Saitoh, Pizzi, Wang: "Perturbation of SUMOlation enzyme Ubc9 by distinct domain within nucleoporin RanBP2/Nup358." in: The Journal of biological chemistry, Vol. 277, Issue 7, pp. 4755-63, (2002) (PubMed).

Starborg, Gell, Brundell, Höög: "The murine Ki-67 cell proliferation antigen accumulates in the nucleolar and heterochromatic regions of interphase cells and at the periphery of the mitotic chromosomes in a process essential for cell cycle progression." in: Journal of cell science, Vol. 109 ( Pt 1), Issue 12, pp. 143-53, (1996) (PubMed).

Synonyms and alternative names related to RPSA/Laminin Receptor

40S ribosomal protein SA (rssa), 67kD laminin receptor (rpsa), ribosomal protein SA (RPSA), ribosomal protein SA (Rpsa), ribosomal protein SA (rpsa), 40S ribosomal protein SA (LOC100144340), 37LRP, 67kDa, 67LR, 67lr, AL022858, DMRT1, LAMBR, LamR, lamR, Lamr, LamR1, LAMR1, Lamr1, lamr1, Lamrl1, LBP, LBP/p40, LRP, LRP/LR, MLR, NEM/1CHD4, p40, P40, P40-3, P40-8, rpsa, RPSA, SA, zgc:55831, zgc:77824

Protein level used designations for RPSA/Laminin Receptor

  • 37 kDa laminin receptor
  • 37/67 kDa laminin receptor
  • 67 kDa laminin receptor
  • Laminin receptor 1
  • Laminin-binding protein precursor p40
  • ribosomal protein SA
  • 40S ribosomal protein SA
  • laminin-binding protein precursor p40
  • 37LRP
  • 67LR
  • LBP/p40
  • LRP/LR
  • lamR
  • colon carcinoma laminin-binding protein
  • laminin receptor 1 (67kD, ribosomal protein SA)
  • multidrug resistance-associated protein MGr1-Ag
  • 37 kDa oncofetal antigen
  • OFA/iLRP
  • P40-3, functional
  • P40-8, functional
  • laminin receptor 1 (ribosomal protein SA)
  • 37kD Laminin receptor
  • laminin receptor 1
  • laminin receptor 1 (ribosomal protein SA, 67 kDA)
  • ribosomal protein SA pseudogene
  • laminin receptor
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