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RPS19 产品

(Ribosomal Protein S19 (RPS19))

Categories

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008].

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Featured RPS19 Categories

RPS19 抗体

High quality antibodies with extensive validation data.

RPS19 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

RPS19 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RPS19 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (5)
Cat. No. ABIN185519
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (5)
  • (3)
Cat. No. ABIN562734
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, ICC, IF
Validations
  • (4)
Cat. No. ABIN6257469
Quantity 100 μL
Datasheet Datasheet

Recommended RPS19 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969965
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959190
Quantity 96 tests
Datasheet Datasheet
Reactivity Chicken
Analytical Method Quantitative
Validations
Cat. No. ABIN1058156
Quantity 96 tests
Datasheet Datasheet

Recommended RPS19 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1318761
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1318760
Quantity 25 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3128755
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our RPS19 Products

Singh, Goldberg, Henson, Husain-Krautter, Nihrane, Blanc, Ellis, Lipton, Liu: "p53-Independent cell cycle and erythroid differentiation defects in murine embryonic stem cells haploinsufficient for Diamond Blackfan anemia-proteins: RPS19 versus RPL5." in: PLoS ONE, Vol. 9, Issue 2, pp. e89098, (2014) (PubMed).

Aspesi, Pavesi, Robotti, Crescitelli, Boria, Avondo, Moniz, Da Costa, Mohandas, Roncaglia, Ramenghi, Ronchi, Gustincich, Merlin, Marengo, Ellis, Follenzi, Santoro, Dianzani: "Dissecting the transcriptional phenotype of ribosomal protein deficiency: implications for Diamond-Blackfan Anemia." in: Gene, Vol. 545, Issue 2, pp. 282-9, (2014) (PubMed).

Caterino, Corbo, Imperlini, Armiraglio, Pavesi, Aspesi, Loreni, Dianzani, Ruoppolo: "Differential proteomic analysis in human cells subjected to ribosomal stress." in: Proteomics, Vol. 13, Issue 7, pp. 1220-7, (2013) (PubMed).

Sezgin, Henson, Nihrane, Singh, Wattenberg, Alard, Ellis, Liu: "Impaired growth, hematopoietic colony formation, and ribosome maturation in human cells depleted of Shwachman-Diamond syndrome protein SBDS." in: Pediatric blood & cancer, Vol. 60, Issue 2, pp. 281-6, (2012) (PubMed).

Rey, Duffy, Brown, Kennedy, Dick, Dror, Tailor: "Enhanced alternative splicing of the FLVCR1 gene in Diamond Blackfan anemia disrupts FLVCR1 expression and function that are critical for erythropoiesis." in: Haematologica, Vol. 93, Issue 11, pp. 1617-26, (2008) (PubMed).

Léger-Silvestre, Caffrey, Dawaliby, Alvarez-Arias, Gas, Bertolone, Gleizes, Ellis: "Specific Role for Yeast Homologs of the Diamond Blackfan Anemia-associated Rps19 Protein in Ribosome Synthesis." in: The Journal of biological chemistry, Vol. 280, Issue 46, pp. 38177-85, (2005) (PubMed).

Synonyms and alternative names related to RPS19

30S ribosomal protein S19 (rps19), 40S ribosomal protein S19 (rps-19), ribosomal protein S19 (RPS19), ribosomal protein S19 (Rps19), DBA, DBA1, Dsk3, S19

Protein level used designations for RPS19

  • ribosomal protein S19
  • 40S ribosomal protein S19
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