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RPL7A 产品

(Ribosomal Protein L7a (RPL7A))

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Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L7AE family of ribosomal proteins. It can interact with a subclass of nuclear hormone receptors, including thyroid hormone receptor, and inhibit their ability to transactivate by preventing their binding to their DNA response elements. This gene is included in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity. It is co-transcribed with the U24, U36a, U36b, and U36c small nucleolar RNA genes, which are located in its second, fifth, fourth, and sixth introns, respectively. This gene rearranges with the trk proto-oncogene to form the chimeric oncogene trk-2h, which encodes an oncoprotein consisting of the N terminus of ribosomal protein L7a fused to the receptor tyrosine kinase domain of trk. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008].

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Featured RPL7A Categories

RPL7A 抗体

High quality antibodies with extensive validation data.

RPL7A 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RPL7A 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN6147151
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF
Validations
  • (3)
Cat. No. ABIN7257329
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC
Validations
  • (3)
Cat. No. ABIN6147150
Quantity 100 μL
Datasheet Datasheet

Recommended RPL7A ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6207398
Quantity 96 tests
Datasheet Datasheet

Recommended RPL7A 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1318667
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3087282
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3132929
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our RPL7A Products

El Fatimy, Davidovic, Tremblay, Jaglin, Dury, Robert, De Koninck, Khandjian: "Tracking the Fragile X Mental Retardation Protein in a Highly Ordered Neuronal RiboNucleoParticles Population: A Link between Stalled Polyribosomes and RNA Granules." in: PLoS genetics, Vol. 12, Issue 7, pp. e1006192, (2016) (PubMed).

McCoy, Poliquin-Duchesneau, Corbin: "Molecular dynamics of FMRP and other RNA-binding proteins in MEG-01 differentiation: the role of mRNP complexes in non-neuronal development." in: Biochemistry and cell biology = Biochimie et biologie cellulaire, Vol. 94, Issue 6, pp. 597-608, (2016) (PubMed).

Lauzière, Lessard, Meunier, McCoy, Bergeron, Corbin: "Unusual subcellular confinement of the fragile X mental retardation protein (FMRP) in circulating human platelets: complete polyribosome dissociation." in: Biochimie, Vol. 94, Issue 4, pp. 1069-73, (2012) (PubMed).

Frolova, Gorchakov, Pereboeva, Atasheva, Frolov: "Functional Sindbis virus replicative complexes are formed at the plasma membrane." in: Journal of virology, Vol. 84, Issue 22, pp. 11679-95, (2010) (PubMed).

Synonyms and alternative names related to RPL7A

Ribosomal protein L7A (RpL7A), 60S ribosomal protein L7a (LOC100525692), ribosomal protein L7a (rpl7a), ribosomal protein L7a (RPL7A), ribosomal protein L7A (Rpl7a), ribosomal protein L7a (Rpl7a), CG3314, Dmel\\CG3314, L7A, L7a, Rp L7A, rpl7a, Surf-3/rpL7a, surf3, SURF3, Surf3, Surf3/rpL7a, TRUP, wu:fa95b03, zgc:73183, zgc:86667

Protein level used designations for RPL7A

  • CG3314-PA
  • CG3314-PD
  • RpL7A-PA
  • RpL7A-PD
  • ribosomal protein L7A
  • 60S ribosomal protein L7a
  • Surfeit locus protein 3
  • ribosomal protein L7a
  • PLA-X polypeptide
  • surfeit 3
  • surfeit locus protein 3
  • thyroid hormone receptor uncoupling protein
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