The protein encoded by this gene contains a RING finger motif. The mouse counterpart of this protein has been shown to interact with Rela, the p65 subunit of NF-kappaB (NFKB), and modulate NFKB-mediated transcription activity. The mouse protein also binds ubiquitin-conjugating enzymes (E2s) and is a substrate for E2-dependent ubiquitination. [provided by RefSeq, Jul 2008].
Asamitsu, Tetsuka, Kanazawa, Okamoto: "RING finger protein AO7 supports NF-kappaB-mediated transcription by interacting with the transactivation domain of the p65 subunit." in: The Journal of biological chemistry, Vol. 278, Issue 29, pp. 26879-87, (2003) (PubMed).
Aliases for RNF25 抗体
ring finger protein 25 (RNF25) 抗体 ring finger protein 25 (Rnf25) 抗体 0610009H16Rik 抗体 AO7 抗体