RNF19A 抗体
(Ring Finger Protein 19A (RNF19A))
The protein encoded by this gene contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquitin ligase that is localized in Lewy bodies, a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein binds and ubiquitylates synphilin 1 (SNCAIP) which is an interacting protein of alpha synuclein in neurons and a major component of Lewy bodies. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Feb 2012].
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Latest Publications for our RNF19A 抗体
: "A novel centrosomal ring-finger protein, dorfin, mediates ubiquitin ligase activity." in: Biochemical and biophysical research communications, Vol. 281, Issue 3, pp. 706-13, (2001) (PubMed).Aliases for RNF19A 抗体
ring finger protein 19A, RBR E3 ubiquitin protein ligase (RNF19A) 抗体ring finger protein 19A (Rnf19a) 抗体
ring finger protein 19A, RBR E3 ubiquitin protein ligase (Rnf19a) 抗体
AA032313 抗体
Dorfin 抗体
RNF19 抗体
Rnf19 抗体
RNF19A 抗体
Ubce7ip2 抗体
UIP117 抗体
XYbp 抗体
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