The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene is located in a chromosomal region known to be frequently deleted in patients with neurofibromatosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
Zhao, Li, Bradfield, Zhang, Mentch, Wang, Sleiman, Kim, Glessner, Hou, Keating, Thomas, Garris, Deliard, Frackelton, Otieno, Chiavacci, Berkowitz, Hakonarson, Grant: "The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature." in: BMC medical genetics, Vol. 11, pp. 96, (2010) (PubMed).
You, Sun, Zhou, Sun, Liang, Zhai, Jiang: "PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4." in: Nature immunology, Vol. 10, Issue 12, pp. 1300-8, (2009) (PubMed).
Oshiumi, Matsumoto, Hatakeyama, Seya: "Riplet/RNF135, a RING finger protein, ubiquitinates RIG-I to promote interferon-beta induction during the early phase of viral infection." in: The Journal of biological chemistry, Vol. 284, Issue 2, pp. 807-17, (2009) (PubMed).
Aliases for RNF135 抗体
ring finger protein 135 (RNF135) 抗体 ring finger protein 135 (Rnf135) 抗体 0610037N03Rik 抗体 2410006N06Rik 抗体 LRRGT00184 抗体 MMFD 抗体 REUL 抗体 Riplet 抗体