RLIM 抗体
(Ring Finger Protein, LIM Domain Interacting (RLIM))
The protein encoded by this gene is a RING-H2 zinc finger protein. It has been shown to be an E3 ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Feb 2009].
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Latest Publications for our RLIM 抗体
: "E3 Ubiquitin Ligase RLIM Negatively Regulates c-Myc Transcriptional Activity and Restrains Cell Proliferation." in: PLoS ONE, Vol. 11, Issue 9, pp. e0164086, (2016) (PubMed).: "Nuclear receptor NR4A1 promotes breast cancer invasion and metastasis by activating TGF-? signalling." in: Nature communications, Vol. 5, pp. 3388, (2014) (PubMed).
: "The role of maternal-specific H3K9me3 modification in establishing imprinted X-chromosome inactivation and embryogenesis in mice." in: Nature communications, Vol. 5, pp. 5464, (2014) (PubMed).
: "RNF12 is an X-Encoded dose-dependent activator of X chromosome inactivation." in: Cell, Vol. 139, Issue 5, pp. 999-1011, (2009) (PubMed).
: "Ubiquitin Ligase RLIM Modulates Telomere Length Homeostasis through a Proteolysis of TRF1." in: The Journal of biological chemistry, Vol. 284, Issue 13, pp. 8557-66, (2009) (PubMed).
: "Phosphopeptide enrichment by aliphatic hydroxy acid-modified metal oxide chromatography for nano-LC-MS/MS in proteomics applications." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 6, pp. 1103-9, (2007) (PubMed).
: "Selective degradation of excess Ldb1 by Rnf12/RLIM confers proper Ldb1 expression levels and Xlim-1/Ldb1 stoichiometry in Xenopus organizer functions." in: Development (Cambridge, England), Vol. 130, Issue 17, pp. 4161-75, (2003) (PubMed).
: "Ubiquitination-dependent cofactor exchange on LIM homeodomain transcription factors." in: Nature, Vol. 416, Issue 6876, pp. 99-103, (2002) (PubMed).
Aliases for RLIM 抗体
ring finger protein, LIM domain interacting (RLIM) 抗体ring finger protein, LIM domain interacting (Rlim) 抗体
XRnf12C protein (xrnf12c) 抗体
ring finger protein, LIM domain interacting (rlim) 抗体
AL022832 抗体
AW743871 抗体
Ha1r 抗体
NY-REN-43 抗体
R-LIM 抗体
RNF12 抗体
Rnf12 抗体
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