Splicing Factor 3a, Subunit 1 蛋白

蛋白简介

This gene encodes subunit 1 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 1 belongs to the SURP protein family\; named for the SURP (also called SWAP or Suppressor-of-White-APricot) motifs that are thought to mediate RNA binding. Subunit 1 has tandemly repeated SURP motifs in its amino-terminal half while its carboxy-terminal half contains a proline-rich region and a ubiquitin-like domain. Binding studies with truncated subunit 1 derivatives demonstrated that the two SURP motifs are necessary for binding to subunit 3 while contacts with subunit 2 may occur through sequences carboxy-terminal to the SURP motifs. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with Splicing Factor 3a, Subunit 1 (SF3A1)

• CG16941 gene product from transcript CG16941-RA (CG16941) 抗体
• SWAP/Surp domain-containing protein (sf3a1) 抗体
• splicing factor 3a, subunit 1 (sf3a1) 抗体
• splicing factor 3a, subunit 1 (spl1) 抗体
• splicing factor 3a, subunit 1 (Sf3a1) 抗体
• 显示所有的基因名称
• splicing factor 3a subunit 1 (SF3A1) 抗体

• 1200014H24Rik 抗体
• 5930416L09Rik 抗体
• AI159724 抗体
• DDBDRAFT_0168938 抗体
• DDBDRAFT_0233180 抗体
• 显示所有的同义词和别名
• DDB_0168938 抗体
• DDB_0233180 抗体
• Dmel\\CG16941 抗体
• PRP21 抗体
• PRPF21 抗体
• SAP114 抗体
• SF3a1 抗体
• SF3A120 抗体
• si:dz150f13.2 抗体
• wu:fc38e01 抗体
• wu:fc50a11 抗体
• wu:fj37c05 抗体
• zgc:65786 抗体

Protein level used designations for SF3A1

CG16941-PA , splicing factor 3a, subunit 1 , splicing factor 3A subunit 1 , ubiquitin domain-containing protein , Splicing factor 3 subunit 1 , SF3a120 , splicing factor 3 subunit 1 , splicing factor 3a, subunit 1, 120kDa , SAP 114 , pre-mRNA processing 21 , pre-mRNA splicing factor SF3a (120 kDa subunit) , spliceosome-associated protein 114