This gene encodes a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation. A non-coding transcript variant of this gene results from naturally occurring read-through transcription between this locus and the neighboring DUSP5P (dual specificity phosphatase 5 pseudogene) locus.[provided by RefSeq, Mar 2011].
Tao, Pennica, Xu, Kalejta, Levine: "Wrch-1, a novel member of the Rho gene family that is regulated by Wnt-1." in: Genes & development, Vol. 15, Issue 14, pp. 1796-807, (2001) (PubMed).
Aliases for RHOU 抗体
ras homolog family member U (RHOU) 抗体 ras homolog family member U (Rhou) 抗体 ras homolog gene family, member U (RHOU) 抗体 ras homolog family member U (rhou) 抗体 ras homolog family member Ua (rhoua) 抗体 ras homolog family member Ub (rhoub) 抗体 ras homolog family member U L homeolog (rhou.L) 抗体 2310026M05Rik 抗体 AI182090 抗体 ARHU 抗体 Arhu 抗体 arhu 抗体 CDC42L1 抗体 cdc42l1 抗体 DJ646B12.2 抗体 fJ646B12.2 抗体 fj646b12.2 抗体 G28K 抗体 hG28K 抗体 hg28k 抗体 mG28K 抗体 MGC107947 抗体 rac-2 抗体 rhou 抗体 Wrch 抗体 WRCH-1 抗体 wrch-1 抗体 WRCH1 抗体 wrch1 抗体 wu:fb18g01 抗体 xg28k 抗体 zgc:101642 抗体 zgc:110357 抗体