This gene encodes one of the many small GTP-binding proteins in the Rho family shown to be associated with focal adhesions in endothelial cells (PMID: 21148427, 22103495). The encoded protein is activated by vascular endothelial growth factor and may regulate angiogenesis. [provided by RefSeq, Dec 2011].
Ho, Aruri, Kapadia, Mehr, White, Ganesan: "RhoJ regulates melanoma chemoresistance by suppressing pathways that sense DNA damage." in: Cancer research, Vol. 72, Issue 21, pp. 5516-28, (2012) (PubMed).
Fukushima, Okada, Kataoka, Hirashima, Yoshida, Mann, Gomi, Nishida, Nishikawa, Uemura: "Sema3E-PlexinD1 signaling selectively suppresses disoriented angiogenesis in ischemic retinopathy in mice." in: The Journal of clinical investigation, Vol. 121, Issue 5, pp. 1974-85, (2011) (PubMed).
Aliases for RHOJ 抗体
ras homolog family member J (RHOJ) 抗体 ras homolog family member J L homeolog (rhoj.L) 抗体 ras homolog family member J (rhoj) 抗体 ras homolog family member J (Rhoj) 抗体 1110005O19Rik 抗体 arhj 抗体 ARHJ 抗体 Arhj 抗体 AW210585 抗体 MGC83410 抗体 rasl7b 抗体 RASL7B 抗体 RHOJ 抗体 si:dkey-100h21.1 抗体 tc10b 抗体 TC10B 抗体 TC10L 抗体 TCL 抗体