This gene is a member of the regulator of G protein signaling (RGS) family and encodes a protein with a single RGS domain. Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. They accelerate transit through the cycle of GTP binding and hydrolysis to GDP, thereby terminating signal transduction, but paradoxically, also accelerate receptor-stimulated activation. [provided by RefSeq, Jul 2008].
Paul, Dansithong, Figueroa, Scoles, Pulst: "Staufen1 links RNA stress granules and autophagy in a model of neurodegeneration." in: Nature communications, Vol. 9, Issue 1, pp. 3648, (2018) (PubMed).
Scoles, Meera, Schneider, Paul, Dansithong, Figueroa, Hung, Rigo, Bennett, Otis, Pulst: "Antisense oligonucleotide therapy for spinocerebellar ataxia type 2." in: Nature, Vol. 544, Issue 7650, pp. 362-366, (2017) (PubMed).
Dansithong, Paul, Figueroa, Rinehart, Wiest, Pflieger, Scoles, Pulst: "Ataxin-2 regulates RGS8 translation in a new BAC-SCA2 transgenic mouse model." in: PLoS genetics, Vol. 11, Issue 4, pp. e1005182, (2015) (PubMed).
Aliases for RGS8 抗体
regulator of G protein signaling 8 (RGS8) 抗体 regulator of G-protein signaling 8 (Rgs8) 抗体 regulator of G protein signaling 8 (rgs8) 抗体 6530413N01Rik 抗体 zgc:92913 抗体