The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008].
Alba-Delgado, Borges, Sánchez-Blázquez, Ortega, Horrillo, Mico, Meana, Neto, Berrocoso: "The function of alpha-2-adrenoceptors in the rat locus coeruleus is preserved in the chronic constriction injury model of neuropathic pain." in: Psychopharmacology, Vol. 221, Issue 1, pp. 53-65, (2012) (PubMed).
Aliases for RGS11 抗体
regulator of G protein signaling 11 (RGS11) 抗体 regulator of G-protein signaling 11 (Rgs11) 抗体 regulator of G-protein signaling 11 L homeolog (rgs11.L) 抗体 regulator of G-protein signaling 11 (RGS11) 抗体 C78048 抗体 rgs9-a 抗体 RS11 抗体 XRGSIV 抗体