抗Rat (Rattus) Myogenin 抗体:
抗Mouse (Murine) Myogenin 抗体:
抗Human Myogenin 抗体:
Human Monoclonal Myogenin Primary Antibody for ICC, IHC (fro) - ABIN252474
Wang, Marx, McNutt, Rutledge, Gown: Expression of myogenic regulatory proteins (myogenin and MyoD1) in small blue round cell tumors of childhood. in The American journal of pathology 1996
Show all 5 Pubmed References
Human Monoclonal Myogenin Primary Antibody for FACS - ABIN4895772
Kelc, Trapecar, Gradisnik, Rupnik, Vogrin: Platelet-rich plasma, especially when combined with a TGF-β inhibitor promotes proliferation, viability and myogenic differentiation of myoblasts in vitro. in PLoS ONE 2015
Show all 2 Pubmed References
Human Monoclonal Myogenin Primary Antibody for IF, IHC (p) - ABIN531977
Dias, Chen, Dilday, Palmer, Hosoi, Singh, Wu, Li, Thompson, Parham, Qualman, Houghton: Strong immunostaining for myogenin in rhabdomyosarcoma is significantly associated with tumors of the alveolar subclass. in The American journal of pathology 2000
Cat (Feline) Monoclonal Myogenin Primary Antibody for IHC (fro), IF - ABIN535201
Hasty, Bradley, Morris, Edmondson, Venuti, Olson, Klein: Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin gene. in Nature 1993
Show all 3 Pubmed References
muscle-specific expression of myogenin in zebrafish embryos is controlled by multiple regulatory elements in the promoter
The results show that myogenin gene expression is more sensitive to nutrient conditions of fish than traditional indicators such as the RNA/DNA ratio.
myog cannot rescue myogenesis in the myod/myf5 double morphant
Autophagy proteins were measured to understand the molecule mechanisms. We also inhibited hypoxic autophagy and examined the changes in myogenin expression, myotubes formation, and apoptosis.
The ELF-EMFs did not affect C2C12 myoblast viability or proliferation rate. Conversely, at ELF-EMF intensity in the mT range, the myogenic process was accelerated, through increased expression of MyoD, myogenin, and connexin 43
Data show that MyoD and myogenin associate with distinct chromatin states.
The study demonstrates an essential role of Setd2 in myoblast proliferation and differentiation, and uncovers Setd2-mediated molecular mechanism through regulating MyoG and p21.
Overexpression and knockdown of TLP revealed that the levels of muscle-specific myosin heavy chain and the myogenic transcription factor myogenin are downregulated by TLP. The proximal AT-rich sequence of the myogenin promoter is responsible for TLP-mediated transcriptional repression.
This suggests that 4.1R may influence myogenesis by preventing VHL-mediated myogenin degradation.
Findings indicate a interplay between A-kinase anchoring protein 6 (AKAP6) and myogenin.
In summary, our results implicate that metastatic properties of some RMS subtypes might be linked to c-Myb function.
The Myf5- and Myogenin-deficient mice showed a partial or complete, respectively, loss of TMC in an otherwise regularly structured thymus.
Dach2 and Hdac9 mediate the effects of muscle activity on muscle reinnervation; Myog and Gdf5 appear to stimulate muscle reinnervation through parallel pathways
Combining chemical with mechanical factor increases expression and there was no significant difference in MyoG expression of ESCs- and MSCs-chemical + mechanical groups
TWIST reverses muscle cell differentiation through promoter binding and down-regulation of myogenin.
miR-186 inhibits muscle cell differentiation through myogenin regulation.
P38alpha-defective, Myog-expressing myoblasts fail to form multinucleated myotubes.
Extensive MyoD and MyoG occupancy in the extragenic regions. RNA synthesis at MyoD+/MyoG+ extragenic enhancer sites.
Expression of myogenin probably influences the shift from glycolytic metabolism towards oxidative metabolism in differentiating myoblasts.
Myogenin expression and myogenesis were nearly abolished in the absence of both AMPKalpha1 and AMPKalpha2, while enhanced AMPK activity promoted myogenesis and myotube formation.
data demonstrated that AMPKalpha1 but not AMPKalpha2 stimulates myogenin expression and myogenesis via phosphorylation of HDAC5 at Ser 259 and 498, which provides an important mechanisms linking AMPK to myogenic differentiation
PI3K and AKT regulated skeletal muscle differentiation by regulating the expression of Myogenin and MCK.
These findings indicated that TFE3 has a regulatory role in myoblast differentiation, and that transcriptional suppression of myogenin expression may be part of the mechanism of action.
Among these targets, dehydrogenase/reductase member 2 DHRS2 and MYO1B were directly regulated by miR1453p in esophageal squamous cell carcinoma (ESCC) cells by dual luciferase reporter assays. Aberrantly expressed DHRS2 and MYOIB were detected in ESCC clinical specimens, and their overexpression enhanced cancer cell aggressiveness.
results indicate that myogenin is a positive regulator in transcriptional regulation of MEGF10 in skeletal muscle
Sustained GSK3beta activity represses a critical regulatory step in the myogenic cascade, contributing to the undifferentiated, proliferative phenotype in alveolar rhabdomyosarcoma.
Our study illustrates that focal myogenin immunoreactivity occurs uncommonly in fibroepithelial polyps of the lower female genital tract.
Data indicate that muscle MYOG mRNA expression doubled, whereas MSTN protein expression decreased following immobilization.
SREBP-1 regulate muscle protein synthesis through the downregulation of the expression of MYOD1, MYOG and MEF2C factors.
the FACT complex promotes myogenin-dependent transcription
Human muscle samples were analysed at different time-points post-denervation to evaluate changes in myogenin expression and their relationship with skeletal muscle atrophy.
After 2 years of denervation, expression of myogenin protein in myonuclei was decreased, but after 3 years of denervation, no expression of myogenin protein in myonuclei was found in denervated posterior cricoarytenoid muscles.
The physical interaction of CARM1 and PCAF is likely pivotal for the activation of PCAF in the downstream of CARM1 pathway for inducing myogenin under Tetradecanoylphorbol Acetate -induced differentiation.
study showed that a rapid rearrangement of myogenin expression occurs in exercised human skeletal muscles in response to a single bout of exercise
myogenin and myocyte enhancer factor-2 expression are triggered by membrane hyperpolarization during human myoblast differentiation
induction of Id1 not only blocks transcriptional activity but also induces myogenin degradation by blocking formation of myogenin-E47 protein complexes.
there is a functional link between dysferlin and myogenin in the differentiation of skeletal muscle
Myogenin and myogenic differentiation factor D (MyoD) mRNAs increased (P < 0.05) in young and old, whereas myogenic factor (myf)-5 mRNA increased in young only (P < 0.05). Myf-6 protein increased (P < 0.05) in both young and old.
MYOG is a positive diagnostic for biliary tract rhabdomyosarcoma.
MYOG had positive staining in this melanotic neuroectodermal tumor.
Both PCAF and BRG1 are also involved in the activation of the myogenin gene in rhabdomyosarcoma
transcription of Cugbp1 gene in muscle is regulated by myogenin and E proteins
Studied the effects of microRNA-27a on myogenin expression and the Akt/FoxO1 signal pathway during porcine myoblast differentiation. Overexpression of miR-27a suppressed myogenin expression during porcine myoblast differentiation, whereas inhibition of miR-27a promoted the mRNA and protein expression levels of myogenin; overexpression of miR-27a decreased the level of P-Akt/Akt and increased the protein level of FoxO1.
the MyoG gene is very conservative and there are very few mutation sites between different breeds
mutation in exon 1 of the MYOG gene had no statistically significant association with carcass quality traits
Significant differences were found in the birth weight and the backfat thickness among the different MyoG genotypes
Relative MYOD1 expression was not different, but MYOG expression was higher in the (ligated-tube)crowded group embryos.
overexpression of DEC1 blocked myogenesis by inhibiting MyoG promoter activity in bovine.
MiR-2425-5p targets RAD9A and MYOG to regulate the proliferation and differentiation of bovine skeletal muscle-derived satellite cells.
EGR1 can promote skeletal muscle satellite cell differentiation through positive regulation of MyoG gene expression.
data suggested that miR-2400 could promote MDSCs proliferation through targeting MYOG
the MyoG SNP has potential as a genetic marker for economically relevant body measurement traits in native Chinese cattle breeds.
Studied and compared mRNA levels of myostatin (MSTN), myogenin (MyoG), and myosin heavy chain (MyHC) in skeletal muscles of two rabbit breeds with different body sizes and growth rates.
Myogenin is a muscle-specific transcription factor that can induce myogenesis in a variety of cell types in tissue culture. It is a member of a large family of proteins related by sequence homology, the helix-loop-helix (HLH) proteins. It is essential for the development of functional skeletal muscle.
, myogenin (myogenic factor 4)
, MYOD1-related protein
, class C basic helix-loop-helix protein 3
, myogenic factor 4
, myogenic factor