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抗Rat (Rattus) Tumor Protein p73 抗体:
抗Human Tumor Protein p73 抗体:
抗Mouse (Murine) Tumor Protein p73 抗体:
Human Monoclonal Tumor Protein p73 Primary Antibody for ChIP, CyTOF - ABIN4343232
Shimodaira, Yoshioka-Yamashita, Kolodner, Wang: Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin. in Proceedings of the National Academy of Sciences of the United States of America 2003
Show all 49 Pubmed References
Human Monoclonal Tumor Protein p73 Primary Antibody for ChIP, ICC - ABIN252619
Costanzo, Merlo, Pediconi, Fulco, Sartorelli, Cole, Fontemaggi, Fanciulli, Schiltz, Blandino, Balsano, Levrero: DNA damage-dependent acetylation of p73 dictates the selective activation of apoptotic target genes. in Molecular cell 2002
Show all 27 Pubmed References
Human Polyclonal Tumor Protein p73 Primary Antibody for IHC (p), IP - ABIN151880
Levy, Adamovich, Reuven, Shaul: The Yes-associated protein 1 stabilizes p73 by preventing Itch-mediated ubiquitination of p73. in Cell death and differentiation 2007
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Human Monoclonal Tumor Protein p73 Primary Antibody for IP, WB - ABIN967629
Jost, Marin, Kaelin: p73 is a simian [correction of human] p53-related protein that can induce apoptosis. in Nature 1997
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Human Monoclonal Tumor Protein p73 Primary Antibody for IP, WB - ABIN967628
Zhu, Jiang, Zhou, Chen: The potential tumor suppressor p73 differentially regulates cellular p53 target genes. in Cancer research 1998
Show all 5 Pubmed References
Human Monoclonal Tumor Protein p73 Primary Antibody for IP, WB - ABIN967630
De Laurenzi, Costanzo, Barcaroli, Terrinoni, Falco, Annicchiarico-Petruzzelli, Levrero, Melino: Two new p73 splice variants, gamma and delta, with different transcriptional activity. in The Journal of experimental medicine 1998
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Human Monoclonal Tumor Protein p73 Primary Antibody for WB - ABIN252620
Shao, Tanaka, Gribi, Yu: Thioredoxin-related regulation of NO/NOS activities. in Annals of the New York Academy of Sciences 2002
Human Monoclonal Tumor Protein p73 Primary Antibody for GS, ICC - ABIN269466
King, Reddi, Ponnamperuma, Gerdes, Weinberg: Dysregulated ΔNp63α negatively regulates the maspin promoter in keratinocytes via blocking endogenous p73 binding. in Molecular carcinogenesis 2014
Human Polyclonal Tumor Protein p73 Primary Antibody for IHC - ABIN966779
Yuan, Shioya, Ishiko, Sun, Gu, Huang, Lu, Kharbanda, Weichselbaum, Kufe: p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage. in Nature 1999
p73 supports mitochondria respiration in medulloblastoma via regulation of glutamine (显示 GFPT1 抗体) metabolism
Study suggests that the cleavage of p73 on specific sites may release its pro-apoptotic function and contribute to cell death in breast cancer.
the transactivation inhibitory (TI) domains within the alpha-isoform-specific C termini of p63 (显示 RPE65 抗体) and p73 are essential for binding to p53R175H.
High TP73 expression is associated with glioblastoma cell invasion.
In the present study, we provide evidence that the tumor suppressor gene p73 is highly susceptible to Mn-induced neurotoxicity in the nigrostriatal system.
HECW2 (显示 HECW2 抗体) is an ubiquitin ligase that stabilises p73, a crucial mediator of neurodevelopment and neurogenesis. This study implicates pathogenic genetic variants in HECW2 (显示 HECW2 抗体) as potential causes of neurodevelopmental disorders in humans.
Imbalance of the apoptosis pathway, with dysregulation of p73 and TRAIL, seems to play a role in the oncogenesis of odontogenic tumors
High TP73 expression is associated with Metastasis of Hepatocellular Carcinoma.
The reduction of tumor protein p63 (显示 TP63 抗体) and tumor protein p73 isoforms, rather than alteration of DeltaN isoform expression, exerted a significant functional repercussion on cell death and proliferation in hepatitis B virus -expressing HepB cells.
p73 is epigenetically silenced in chondrosarcoma due to promoter methylation, which suggests the utility of p73 methylation as a biomarker.
Absence of TAp73 leads to activation of TGF-beta (显示 TGFB1 抗体) signaling through a Sma (显示 ACTA2 抗体) and Mad-related proteins-independent pathway, favoring oncogenic transforming growth factor-beta effects and epithelial-to-mesenchymal transition.
Findings reinforce the role of TAp73 as tumor suppressor gene and indicate that the regulation of cellular metabolism by TAp73 contributes to its tumor suppressor function.
cells expressing both p63 (显示 CKAP4 抗体) and p73 (显示 ARHGAP24 抗体) exist in mouse epidermis and hair follicle and that hetero-tetramer complexes can be detected by immunoprecipitation in differentiating keratinocytes.
both p53 (显示 TP53 抗体) and p73 (显示 ARHGAP24 抗体) are critical in apoptosis induced by DNA damage and differentiation.
New function of p73 (显示 ARHGAP24 抗体), independent of p53 (显示 TP53 抗体), in the neurogenic architecture of the SVZ of rodent brain.
these results therefore highlight an unanticipated role for p53 (显示 TP53 抗体) family proteins in a regulatory network that integrates essential Wnt (显示 WNT2 抗体)-Tcf (显示 HNF4A 抗体) and nodal-Smad (显示 SMAD1 抗体) inputs.
TAp73 as necessary and sufficient for basal body docking, axonemal extension, and motility during the differentiation of Motile multiciliated cell progenitors.
p73 (显示 ARHGAP24 抗体) drives multiciliogenesis, both through transcriptional activation of a master ciliogenesis transcription factor FoxJ1 (显示 FOXJ1 抗体) and through regulation of multiple genes central to ciliogenesis.
The p73 (显示 ARHGAP24 抗体) acts as a critical regulator of multiciliogenesis in its capacity as a sequence-specific transcription factor, through genomic binding and regulation of genes.
Data show that the Mdm4 (显示 MDM4 抗体)-p73 (显示 ARHGAP24 抗体) axis cannot override the dominant role of p53 (显示 TP53 抗体) in development and tumorigenesis and that Mdm4 (显示 MDM4 抗体) and p73 (显示 ARHGAP24 抗体) interaction during development and tumorigenesis suggests new insight into the role of p53 (显示 TP53 抗体) family members.
ARHGAPs, such as ARHGAP24, encode negative regulators of Rho GTPases (see ARHA\; MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration (Katoh and Katoh, 2004
transformation related protein 73
, tumor protein p73
, tumor protein p73-like
, p53-like transcription factor
, p53-related protein
, RAC1- and CDC42-specific GTPase-activating protein of 72 kDa
, filamin-A-associated RhoGAP
, rho GTPase-activating protein 24
, rho-type GTPase-activating protein 24
, rhoGAP of 73 kDa
, sarcoma antigen NY-SAR-88