JMY 蛋白
(Junction Mediating and Regulatory Protein, P53 Cofactor (JMY))
Acts both as a nuclear p53/TP53-cofactor and a cytoplasmic regulator of actin dynamics depending on conditions. In nucleus, acts as a cofactor that increases p53/TP53 response. Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage. In cytoplasm, acts as a nucleation-promoting factor for both branched and unbranched actin filaments. Activates the Arp2/3 complex to induce branched actin filament networks. Also catalyzes actin polymerization in the absence of Arp2/3, creating unbranched filaments. Contributes to cell motility by controlling actin dynamics.
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6 results
JMY
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
Greater than 95 % as determined by SDS-PAGE
ELISA, WB
1 image
custom-made
JMY
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
JMY
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
JMY
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Aliases for JMY 蛋白
junction mediating and regulatory protein, p53 cofactor (JMY) 蛋白junction mediating and regulatory protein, p53 cofactor (jmy) 蛋白
junction-mediating and regulatory protein (Jmy) 蛋白
WHDC1L3 蛋白
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