Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) 抗体
(Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A))
Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.
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Latest Publications for our Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) 抗体
: "The ins and outs of tRNA transport." in: EMBO reports, Vol. 8, Issue 6, pp. 547-9, (2007) (PubMed).: "An RNA-binding respiratory component mediates import of type II tRNAs into Leishmania mitochondria." in: The Journal of biological chemistry, Vol. 281, Issue 35, pp. 25270-7, (2006) (PubMed).
: "Mammalian Ric-8A (synembryn) is a heterotrimeric Galpha protein guanine nucleotide exchange factor." in: The Journal of biological chemistry, Vol. 278, Issue 10, pp. 8356-62, (2003) (PubMed).
: "Human brain synembryn interacts with Gsalpha and Gqalpha and is translocated to the plasma membrane in response to isoproterenol and carbachol." in: Journal of cellular physiology, Vol. 195, Issue 2, pp. 151-7, (2003) (PubMed).
Aliases for Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) 抗体
RIC8 guanine nucleotide exchange factor A (RIC8A) 抗体RIC8 guanine nucleotide exchange factor A (Ric8a) 抗体
RIC8 guanine nucleotide exchange factor A (ric8a) 抗体
microRNA 6743 (MIR6743) 抗体
synembryn-A (Tsp_08768) 抗体
RIC8 guanine nucleotide exchange factor A L homeolog (ric8a.L) 抗体
CG15797 gene product from transcript CG15797-RB (ric8a) 抗体
synembryn (LOC411841) 抗体
RIC8 guanine nucleotide exchange factor A S homeolog (ric8a.S) 抗体
Synembryn (ric-8) 抗体
RIC8 guanine nucleotide exchange factor B (ric8b) 抗体
AI114950 抗体
CG15797 抗体
Dmel\\CG15797 抗体
DmRic8 抗体
fj97c10 抗体
l(1)G0397 抗体
RIC-8 抗体
ric-8 抗体
Ric-8 抗体
Ric-8A 抗体
ric-8a 抗体
RIC8 抗体
Ric8 抗体
ric8 抗体
Ric8a 抗体
ric8a 抗体
ric8ab 抗体
ricc8aa 抗体
Syn 抗体
synbl 抗体
synembryn 抗体
wu:fj97c10 抗体
xtric-8 抗体
zgc:92294 抗体
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