(Ras Association (RalGDS/AF-6) Domain Family (N-terminal) Member 8 (RASSF8))
This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12\;22)(p11.2\;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011].
Falvella, Spinola, Manenti, Conti, Pastorino, Skaug, Haugen, Dragani: "Common polymorphisms in D12S1034 flanking genes RASSF8 and BHLHB3 are not associated with lung adenocarcinoma risk." in: Lung cancer (Amsterdam, Netherlands), Vol. 56, Issue 1, pp. 1-7, (2007) (PubMed).
Aliases for RASSF8 抗体
Ras association domain family member 8 (RASSF8) 抗体 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8b (rassf8b) 抗体 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 (Rassf8) 抗体 Ras association domain family member 8 (Rassf8) 抗体 5133400D11Rik 抗体 AA815821 抗体 AW123240 抗体 c12orf2 抗体 C12orf2 抗体 HOJ1 抗体 Hoj1 抗体 mHoj-1 抗体 rassf8 抗体 RGD1308820 抗体 wu:fb96e06 抗体 zgc:64017 抗体