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RAF1 蛋白

(V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1))
This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. [provided by RefSeq, Jul 2008].

13 results :

custom-made RAF1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7564914
 
custom-made RAF1 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7555117
 
RAF1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Pubmed 1 reference
产品编号 ABIN7596475
 
RAF1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
产品编号 ABIN1317315
 
RAF1 宿主: 人 宿主: Insect Cells Recombinant 70 % - 90 % Func Active
产品编号 ABIN5509125
 
RAF1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant ELISA, WB, SDS
产品编号 ABIN7579157
 
RAF1 宿主: Hepatitis C Virus (HCV) 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % pure ELISA, WB
产品编号 ABIN2129667
 
RAF1 宿主: Hepatitis C Virus (HCV) 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % pure
产品编号 ABIN935420
 
custom-made RAF1 宿主: 小鼠 宿主: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS
产品编号 ABIN3136985
 
custom-made RAF1 宿主: 人 宿主: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS
产品编号 ABIN3094878
 
RAF1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % SDS
产品编号 ABIN5710215
 
RAF1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2730424
 
RAF1 宿主: 大鼠 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN7585818
 
  • 类型 Protein
    • Protein
  • 应用范围
    • ELISA
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Functional Studies (Func)
    • Standard (STD)
  • 适用
    • Human
    • Hepatitis C Virus (HCV)
    • Mouse
    • Rat
  • 论文引用
  • 图像
  • Carrier free only
  • 抗体来源
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Cell-free protein synthesis (CFPS)
    • Wheat germ
    • Insect Cells
    • Yeast
  • 抗原表位
    • AA 1-648
    • AA 1-130
    • AA 2061-2302
    • full length
  • 标记
    • GST tag
    • His tag
    • Strep Tag
    • His-SUMO Tag
    • Myc-DYKDDDDK Tag
    • 非结合性
  • 蛋白类型
    • Recombinant
  • Format
    • Liquid
    • Lyophilized
  • 生物活性
    • Biologically Active
  • Grade
    • custom-made
  • Supplier
    • antibodies-online
    • CUSABIO
    • OriGene
    • Signalway

Latest Publications for our RAF1 蛋白

Rodríguez-Muñoz, de la Torre-Madrid, Sánchez-Blázquez, Garzón: "NO-released zinc supports the simultaneous binding of Raf-1 and PKC? cysteine-rich domains to HINT1 protein at the mu-opioid receptor." in: Antioxidants & redox signaling, Vol. 14, Issue 12, pp. 2413-25, (2011) (PubMed).

Aliases for RAF1 蛋白

Raf-1 proto-oncogene, serine/threonine kinase (RAF1) 蛋白
Raf-1 proto-oncogene, serine/threonine kinase (Raf1) 蛋白
Raf-1 proto-oncogene, serine/threonine kinase a (raf1a) 蛋白
Raf-1 proto-oncogene, serine/threonine kinase (raf1) 蛋白
v-raf-leukemia viral oncogene 1 (Raf1) 蛋白
Raf-1 proto-oncogene, serine/threonine kinase S homeolog (raf1.S) 蛋白
6430402F14Rik 蛋白
AA990557 蛋白
BB129353 蛋白
c-Raf 蛋白
c-raf 蛋白
CRAF 蛋白
craf 蛋白
cRaf 蛋白
Craf1 蛋白
D830050J10Rik 蛋白
NS5 蛋白
raf 蛋白
Raf-1 蛋白
raf1 蛋白
RAF1 蛋白
v-Raf 蛋白
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