The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. [provided by RefSeq, Jul 2008].
Sugiyama, Kantake, Wu, Kowalczykowski: "Rad52-mediated DNA annealing after Rad51-mediated DNA strand exchange promotes second ssDNA capture." in: The EMBO journal, Vol. 25, Issue 23, pp. 5539-48, (2006) (PubMed).
Aliases for RAD52 抗体
RAD52 homolog, DNA repair protein (RAD52) 抗体 RAD52 homolog, DNA repair protein (Rad52) 抗体 RAD52 homolog, DNA repair protein (rad52) 抗体 RAD52 homolog (S. cerevisiae) (RAD52) 抗体 RAD52 homolog, DNA repair protein S homeolog (rad52.S) 抗体 recombinase (RAD52) 抗体 DNA repair and recombination protein, putative (RAD52) 抗体 RAD52 protein (rad52) 抗体 LOC100223085 抗体 MGC115453 抗体 RAD52 抗体 Rad52yh 抗体 zgc:112400 抗体