May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Functionally cooperates with PALB2 in promoting of D-loop formation by RAD51. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA (By similarity).
Parplys, Zhao, Sharma, Groesser, Liang, Maranon, Leung, Grundt, Dray, Idate, Østvold, Schild, Sung, Wiese: "NUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and genome stability." in: Nucleic acids research, Vol. 43, Issue 20, pp. 9817-34, (2015) (PubMed).
Kovalenko, Golub, Bray-Ward, Ward, Radding: "A novel nucleic acid-binding protein that interacts with human rad51 recombinase." in: Nucleic acids research, Vol. 25, Issue 24, pp. 4946-53, (1998) (PubMed).
Aliases for RAD51AP1 抗体
RAD51 associated protein 1 (Rad51ap1) 抗体 RAD51 associated protein 1 (RAD51AP1) 抗体 2510006L10Rik 抗体 PIR51 抗体 RAB22 抗体