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PUMA 蛋白

(BCL2 Binding Component 3 (BBC3))
This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011].

13 results

custom-made BBC3 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7552527
 
custom-made BBC3 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7552658
 
custom-made BBC3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7560411
 
BBC3 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA
产品编号 ABIN7121980
 
BBC3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Pubmed 1 reference
产品编号 ABIN2730162
 
BBC3 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % as determined by reducing SDS-PAGE. Imm
产品编号 ABIN7504951
 
BBC3 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant WB, SDS, ELISA
产品编号 ABIN7575129
 
BBC3 宿主: 大鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, Imm, PC
产品编号 ABIN7395239
 
custom-made BBC3 宿主: 小鼠 宿主: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA
产品编号 ABIN3128059
 
custom-made BBC3 宿主: 人 宿主: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA
产品编号 ABIN3089700
 
BBC3 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant ~95 % WB, ELISA, MS
产品编号 ABIN2468998
 
BBC3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2730161
 
BBC3 宿主: 大鼠 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN7590721
 
  • 类型 Protein
    • Protein
  • 应用范围
    • ELISA
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • Antibody Production (AbP)
    • Immunogen (Imm)
    • Standard (STD)
    • Mass Spectrometry (MS)
    • Positive Control (PC)
  • 适用
    • Human
    • Mouse
    • Rat
  • 论文引用
  • 图像
  • Carrier free only
  • 抗体来源
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Cell-free protein synthesis (CFPS)
    • Yeast
  • 抗原表位
    • AA 1-193
    • AA 76-170
    • AA 1-261
    • AA 141-261
    • Transcript Variant 1
    • Transcript Variant 4
  • 标记
    • His tag
    • Myc-DYKDDDDK Tag
    • Strep Tag
    • GST tag,His tag
    • His tag,Strep II tag
    • His-IF2DI Tag
  • 蛋白类型
    • Recombinant
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • custom-made
  • Supplier
    • antibodies-online
    • OriGene
    • CUSABIO
    • ProSci

Latest Publications for our PUMA 蛋白

Carpenter, Han, Paw, Lo: "HER2 phosphorylates and destabilizes pro-apoptotic PUMA, leading to antagonized apoptosis in cancer cells." in: PLoS ONE, Vol. 8, Issue 11, pp. e78836, (2013) (PubMed).

Aliases for PUMA 蛋白

BCL2 binding component 3 (BBC3) 蛋白
Bcl-2 binding component 3 (Bbc3) 蛋白
BCL2 binding component 3 (Bbc3) 蛋白
BCL2 binding component 3 (bbc3) 蛋白
BBC3 蛋白
JFY-1 蛋白
JFY1 蛋白
Puma 蛋白
PUMA 蛋白
PUMA/JFY1 蛋白
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