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PUMA 抗体

(BCL2 Binding Component 3 (BBC3))
This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011].
PUMA 抗体  (AA 131-180) PUMA 抗体  (AA 131-180) PUMA 抗体 (AA 131-180) (ABIN731528)

BBC3 适用: 人, 大鼠, Pig WB, ELISA, IP, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

PUMA 抗体  (AA 119-154) PUMA 抗体  (AA 119-154) PUMA 抗体 (AA 119-154) (ABIN3030112)

BBC3 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated

PUMA 抗体  (AA 119-154) PUMA 抗体  (AA 119-154) PUMA 抗体 (AA 119-154) (ABIN388112)

BBC3 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB01353 unconjugated

PUMA 抗体 by Grade

Find PUMA 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

PUMA 抗体 by 适用

Find PUMA 抗体 for a variety of species such as anti-Human PUMA, anti-Rat PUMA, anti-Mouse PUMA. The species listed below are among those available. Click on a link to go to the corresponding products.

PUMA 抗体 by 应用范围

Find PUMA 抗体 validated for a specific application such as WB, ELISA, IHC, FACS. Some of the available applications are listed below. Click on a link to go to the corresponding products.

PUMA 抗体 by 抗体来源

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PUMA 抗体 by 抗原表位

Find PUMA 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

PUMA 抗体 by 克隆形成能力

Find available monoclonal or polyclonal PUMA 抗体. Click on a link to go to the corresponding products.

PUMA 抗体 by 克隆

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PUMA 抗体 by 标记

Find PUMA 抗体 with a specific conjugate such as Biotin, FITC, PE. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular PUMA 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Pig, Rat
Application WB, ELISA, IP, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (3)
  • (4)
Cat. No. ABIN731528
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF, FACS
Validations
  • (6)
Cat. No. ABIN3030112
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, IF, FACS, IHC (p)
Validations
  • (1)
  • (4)
Cat. No. ABIN388112
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF, FACS, IHC (p), EIA
Validations
  • (4)
Cat. No. ABIN356830
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN2565361
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, ICC, IHC (p)
Validations
  • (2)
Cat. No. ABIN213906
Quantity 0.05 mg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN959855
Quantity 0.05 mg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN208703
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN3028491
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, ICC, IP
Validations
  • (1)
Cat. No. ABIN7434332
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7139739
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6242201
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN3186602
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN571246
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN658021
Quantity 400 μL
Datasheet Datasheet

Latest Publications for our PUMA 抗体

Kim, Yu, Chen, Xu, Wu, Todorova, Tang, Feng, Jiang, He, Chen, Fu, Xu: "Wild-Type p53 Promotes Cancer Metabolic Switch by Inducing PUMA-Dependent Suppression of Oxidative Phosphorylation." in: Cancer cell, Vol. 35, Issue 2, pp. 191-203.e8, (2019) (PubMed).

Choi, Koh, Cho, Kim, Kim, Hur: "Temporal and differential regulation of KAISO-controlled transcription by phosphorylated and acetylated p53 highlights a crucial regulatory role of apoptosis." in: The Journal of biological chemistry, Vol. 294, Issue 35, pp. 12957-12974, (2019) (PubMed).

Zhang, Li, Wang, Li, Shi, Kan, Pang: "Inhibition of REST Suppresses Proliferation and Migration in Glioblastoma Cells." in: International journal of molecular sciences, Vol. 17, Issue 5, (2017) (PubMed).

Liao, Chu, Hu, Merkin, Chen, Liu, Degenhardt, White, Ryazanov: "Paradoxical Roles of Elongation Factor-2 Kinase in Stem Cell Survival." in: The Journal of biological chemistry, Vol. 291, Issue 37, pp. 19545-57, (2016) (PubMed).

Su, Shi, Yan, Xi, Su: "Anticancer bioactive peptides suppress human colorectal tumor cell growth and induce apoptosis via modulating the PARP-p53-Mcl-1 signaling pathway." in: Acta pharmacologica Sinica, Vol. 36, Issue 12, pp. 1514-9, (2016) (PubMed).

Vesela, Matalova: "Detection of Bim and Puma in mouse hair follicles using immunofluorescence and TUNEL assay double staining." in: Biotechnic & histochemistry : official publication of the Biological Stain Commission, pp. 1-7, (2015) (PubMed).

Long, Schoonen, Graczyk, OPrey, Ryan: "p73 engages A2B receptor signalling to prime cancer cells to chemotherapy-induced death." in: Oncogene, (2015) (PubMed).

Hui, Yuan, Ren, Jiang: "Nerve growth factor reduces apoptotic cell death in rat facial motor neurons after facial nerve injury." in: Neurosciences (Riyadh, Saudi Arabia), Vol. 20, Issue 1, pp. 65-8, (2015) (PubMed).

Qiu, Cai, Gao, Gu, Liu: "A small peptide derived from p53 linker region can resume the apoptotic activity of p53 by sequestering iASPP with p53." in: Cancer letters, Vol. 356, Issue 2 Pt B, pp. 910-7, (2014) (PubMed).

Sale, Cook: "The BH3 mimetic ABT-263 synergizes with the MEK1/2 inhibitor selumetinib/AZD6244 to promote BIM-dependent tumour cell death and inhibit acquired resistance." in: The Biochemical journal, Vol. 450, Issue 2, pp. 285-94, (2013) (PubMed).

Aliases for PUMA 抗体

BCL2 binding component 3 (BBC3) 抗体
Bcl-2 binding component 3 (Bbc3) 抗体
BCL2 binding component 3 (Bbc3) 抗体
BCL2 binding component 3 (bbc3) 抗体
BBC3 抗体
JFY-1 抗体
JFY1 抗体
Puma 抗体
PUMA 抗体
PUMA/JFY1 抗体
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