PTPRB 产品
(Protein tyrosine Phosphatase, Receptor Type, B (PTPRB))
Categories
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and one intracytoplasmic catalytic domain, thus belongs to receptor type PTP. The extracellular region of this PTP is composed of multiple fibronectin type_III repeats, which was shown to interact with neuronal receptor and cell adhesion molecules, such as contactin and tenascin C. This protein was also found to interact with sodium channels, and thus may regulate sodium channels by altering tyrosine phosphorylation status. The functions of the interaction partners of this protein implicate the roles of this PTP in cell adhesion, neurite growth, and neuronal differentiation. Alternate transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011].
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Featured PTPRB Categories
PTPRB 抗体
High quality antibodies with extensive validation data.
PTPRB ELISA试剂盒
Reliable ELISA kits for a wide range of species.
PTPRB 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PTPRB 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7443743
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7439990
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7444100
Quantity
100 μL
Datasheet
Datasheet
Recommended PTPRB ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962129
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN511536
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Chicken
Analytical Method
Quantitative
Validations
Cat. No.
ABIN1057846
Quantity
96 tests
Datasheet
Datasheet
Recommended PTPRB 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3094830
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3131019
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3094829
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our PTPRB Products
: "SALM4 regulates angiogenic functions in endothelial cells through VEGFR2 phosphorylation at Tyr1175." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 9, pp. 9842-9857, (2020) (PubMed).: "VE-PTP controls blood vessel development by balancing Tie-2 activity." in: The Journal of cell biology, Vol. 185, Issue 4, pp. 657-71, (2009) (PubMed).
Synonyms and alternative names related to PTPRB
protein tyrosine phosphatase, receptor type B (PTPRB), receptor-type tyrosine-protein phosphatase beta (LOC100380677), protein tyrosine phosphatase, receptor type, B (Ptprb), protein tyrosine phosphatase, receptor type B (Ptprb), 3230402H02Rik, C130094E24, HPTP-BETA, HPTPB, PTPB, PTPRB, Ptpz, R-PTP-BETA, Rptpb, VE-PTP, VEPTP, VeptpProtein level used designations for PTPRB
- protein tyrosine phosphatase, receptor type, B
- Receptor-type tyrosine-protein phosphatase beta
- receptor-type tyrosine-protein phosphatase beta-like
- receptor-type tyrosine-protein phosphatase beta
- VE-PTP
- protein tyrosine phosphatase, receptor type, beta polypeptide
- vascular endothelial protein tyrosine phosphatase
- R-PTP-beta
- protein-tyrosine phosphatase beta
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