PTBP1 抗体
(Polypyrimidine Tract Binding Protein 1 (PTBP1))
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| PTBP1 抗体 (AA 1-531) | 人 | 兔 Polyclonal |
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| PTBP1 抗体 | 人 | 兔 Polyclonal |
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| PTBP1 抗体 | 人 | 兔 Monoclonal |
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| PTBP1 抗体 (AA 1-531) | 人 | 兔 Polyclonal |
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| PTBP1 抗体 (AA 26-55) (PE) | 人 | 兔 Polyclonal |
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| PTBP1 抗体 (AA 26-55) (APC) | 人 | 兔 Polyclonal |
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| PTBP1 抗体 (AA 26-55) (Biotin) | 人 | 兔 Polyclonal |
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| PTBP1 抗体 (AA 26-55) (FITC) | 人 | 兔 Polyclonal |
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| PTBP1 抗体 (AA 26-55) (HRP) | 人 | 兔 Polyclonal |
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| PTBP1 抗体 (AA 26-55) | 人 | 兔 Polyclonal |
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| PTBP1 抗体 (C-Term) | 人, 小鼠, 大鼠, Rodents | 小鼠 Monoclonal |
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| PTBP1 抗体 | 人 | 兔 Polyclonal |
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| PTBP1 抗体 | 人, 小鼠, Hamster | 兔 Monoclonal |
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| PTBP1 抗体 (AA 135-292) (FITC) | 人 | 兔 Polyclonal |
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| PTBP1 抗体 (AA 135-292) (Biotin) | 人 | 兔 Polyclonal |
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| PTBP1 抗体 (AA 135-292) (HRP) | 人 | 兔 Polyclonal |
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| PTBP1 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| PTBP1 抗体 | 人 | 小鼠 Monoclonal |
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| PTBP1 抗体 (AA 26-55) | 人 | 兔 Polyclonal |
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| PTBP1 抗体 (N-Term) | 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-531
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-531
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- PE
- 抗体亚型
- IgG
- 抗原表位
- AA 26-55
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- APC
- 抗体亚型
- IgG
- 抗原表位
- AA 26-55
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 26-55
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- AA 26-55
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- AA 26-55
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 26-55
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人, 小鼠, 大鼠, Rodents
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- C-Term
Primary Antibody
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- AA 135-292
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 135-292
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- AA 135-292
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 26-55
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Latest Publications for our PTBP1 抗体
: "Oroxylin A activates PKM1/HNF4 alpha to induce hepatoma differentiation and block cancer progression." in: Cell death & disease, Vol. 8, Issue 7, pp. e2944, (2018) (PubMed).
: "Hydrogen peroxide alters splicing of soluble guanylyl cyclase and selectively modulates expression of splicing regulators in human cancer cells." in: PLoS ONE, Vol. 7, Issue 7, pp. e41099, (2012) (PubMed).
: "Ancient genome-wide admixture extends beyond the current hybrid zone between Macaca fascicularis and M. mulatta." in: Molecular ecology, Vol. 19, Issue 14, pp. 2884-95, (2010) (PubMed).
: "Hepatitis A virus (HAV) proteinase 3C inhibits HAV IRES-dependent translation and cleaves the polypyrimidine tract-binding protein." in: Journal of viral hepatitis, Vol. 17, Issue 9, pp. 618-23, (2010) (PubMed).
: "Polypyrimidine tract-binding protein interacts with coxsackievirus B3 RNA and influences its translation." in: The Journal of general virology, Vol. 91, Issue Pt 5, pp. 1245-55, (2010) (PubMed).
: "Interactions between PTB RRMs induce slow motions and increase RNA binding affinity." in: Journal of molecular biology, Vol. 397, Issue 1, pp. 260-77, (2010) (PubMed).
: "Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping." in: Molecular cell, Vol. 36, Issue 6, pp. 996-1006, (2010) (PubMed).
: "The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 5, pp. 1894-9, (2010) (PubMed).
: "Dynamic antagonism between ETR-3 and PTB regulates cell type-specific alternative splicing." in: Molecular cell, Vol. 9, Issue 3, pp. 649-58, (2002) (PubMed).
: "Hydrogen peroxide alters splicing of soluble guanylyl cyclase and selectively modulates expression of splicing regulators in human cancer cells." in: PLoS ONE, Vol. 7, Issue 7, pp. e41099, (2012) (PubMed).
: "Ancient genome-wide admixture extends beyond the current hybrid zone between Macaca fascicularis and M. mulatta." in: Molecular ecology, Vol. 19, Issue 14, pp. 2884-95, (2010) (PubMed).
: "Hepatitis A virus (HAV) proteinase 3C inhibits HAV IRES-dependent translation and cleaves the polypyrimidine tract-binding protein." in: Journal of viral hepatitis, Vol. 17, Issue 9, pp. 618-23, (2010) (PubMed).
: "Polypyrimidine tract-binding protein interacts with coxsackievirus B3 RNA and influences its translation." in: The Journal of general virology, Vol. 91, Issue Pt 5, pp. 1245-55, (2010) (PubMed).
: "Interactions between PTB RRMs induce slow motions and increase RNA binding affinity." in: Journal of molecular biology, Vol. 397, Issue 1, pp. 260-77, (2010) (PubMed).
: "Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping." in: Molecular cell, Vol. 36, Issue 6, pp. 996-1006, (2010) (PubMed).
: "The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 5, pp. 1894-9, (2010) (PubMed).
: "Dynamic antagonism between ETR-3 and PTB regulates cell type-specific alternative splicing." in: Molecular cell, Vol. 9, Issue 3, pp. 649-58, (2002) (PubMed).
Aliases for PTBP1 抗体
polypyrimidine tract binding protein 1 (PTBP1) 抗体polypyrimidine tract binding protein 1 S homeolog (ptbp1.S) 抗体
polypyrimidine tract-binding protein (NAEGRDRAFT_80143) 抗体
polypyrimidine tract-binding protein (LOC100285404) 抗体
polypyrimidine tract binding protein 1 (Ptbp1) 抗体
polypyrimidine tract binding protein 1a (ptbp1a) 抗体
polypyrimidine tract binding protein 1 L homeolog (ptbp1.L) 抗体
polypyrimidine tract-binding protein 1 (PTB1) 抗体
polypyrimidine tract-binding protein 1 (LOC100061673) 抗体
AA407203 抗体
AL033359 抗体
ATPTB1 抗体
HNRNP-I 抗体
hnrnp-I 抗体
HNRNPI 抗体
HNRPI 抗体
hnrpi 抗体
POLYPYRIMIDINE TRACT-BINDING 抗体
POLYPYRIMIDINE TRACT-BINDING PROTEIN 1 抗体
polypyrimidine tract-binding protein 1 抗体
pPTB 抗体
PTB 抗体
Ptb 抗体
ptb 抗体
PTB-1 抗体
PTB-T 抗体
PTB2 抗体
PTB3 抗体
PTB4 抗体
ptbp1 抗体
PTBP1 抗体
Pybp 抗体
Pybp1 抗体
Pybp2 抗体
T4P13.16 抗体
T4P13_16 抗体
vgrbp60 抗体
wu:fb99f12 抗体
zgc:110689 抗体
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