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PSMC1 蛋白

(Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 (PSMC1))
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit and a 20S core alpha subunit interact specifically with the hepatitis B virus X protein, a protein critical to viral replication. This subunit also interacts with the adenovirus E1A protein and this interaction alters the activity of the proteasome. Finally, this subunit interacts with ataxin-7, suggesting a role for the proteasome in the development of spinocerebellar ataxia type 7, a progressive neurodegenerative disorder. [provided by RefSeq, Jul 2008].

5 results :

PSMC1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant SDS, WB, ELISA
产品编号 ABIN7579033
 
PSMC1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % SDS, WB, Imm, PC
产品编号 ABIN7414540
 
PSMC1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2729955
 
PSMC1 宿主: 大鼠 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN7585738
 
PSMC1 宿主: 小鸡 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN1642929
 
  • 类型 Protein
    • Protein
  • 应用范围
    • ELISA
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • Antibody Production (AbP)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Standard (STD)
  • 适用
    • Human
    • Chicken
    • Rat
  • 图像
  • Carrier free only
  • 抗体来源
    • Escherichia coli (E. coli)
    • Yeast
    • HEK-293 Cells
  • 抗原表位
    • AA 1-440
    • AA 2-440
  • 标记
    • His tag
    • Myc-DYKDDDDK Tag
  • 蛋白类型
    • Recombinant
  • Format
    • Lyophilized
  • Supplier
    • CUSABIO
    • antibodies-online
    • OriGene

Aliases for PSMC1 蛋白

protease (prosome, macropain) 26S subunit, ATPase 1 (Psmc1) 蛋白
proteasome 26S subunit, ATPase 1 (PSMC1) 蛋白
proteasome 26S subunit, ATPase 1 (Psmc1) 蛋白
AI325227 蛋白
P26s4 蛋白
P26S4 蛋白
p56 蛋白
S4 蛋白
s4 蛋白
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