Thymic Stromal Lymphopoietin Protein (TSLP)
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- 抗原 See all Thymic Stromal Lymphopoietin (TSLP) 蛋白
- Thymic Stromal Lymphopoietin (TSLP)
- 生物活性
- Active
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 序列
- MYDFTNCDFE KIKAAYLSTI SKDLITYMSG TKSTEFNNTV SCSNRPHCLT EIQSLTFNPT AGCASLAKEM FAMKTKAALA IWCPGYSETQ INATQAMKKR RKRKVTTNKC L EQVSQLQG L WRRFNRPL LK Q
- 产品特性
- Fully biologically active when compared to standard. The ED50 as measured by its ability to induce proliferation of human IL-7Rª and human TSLP R co-transfected mouse BaF3 cells is less than 0.3 ng/ml,corresponding to a specific activity of > 3.3×106 units/mg.
- 纯度
- > 98 % by SDS-PAGE and HPLC analyses.
- 内毒素水平
- Level Less than 1EU/µg of rHuTSLP as determined by LAL method
- Top Product
- Discover our top product TSLP 蛋白
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Thymic Stromal Lymphopoietin (TSLP) (AA 29-159) protein (His-Avi Tag)
TSLP 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Thymic Stromal Lymphopoietin (TSLP) (Arg127Ala-Mutant), (Arg130Ala-Mutant) protein (His-Avi Tag,Biotin)TSLP 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Thymic Stromal Lymphopoietin (TSLP) (Arg127Ala-Mutant), (Arg130Ala-Mutant) protein (His-Avi Tag)TSLP 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Thymic Stromal Lymphopoietin (TSLP) (AA 29-159) protein (His tag)TSLP 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Thymic Stromal Lymphopoietin (TSLP) (Active) protein (His tag)TSLP 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE. Active
Thymic Stromal Lymphopoietin (TSLP) (Active) protein (His tag)TSLP 宿主: Cynomolgus 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by reducing SDS-PAGE. Active
Thymic Stromal Lymphopoietin (TSLP) (AA 29-159) (Active) protein (His tag)TSLP 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Thymic Stromal Lymphopoietin (TSLP) (AA 29-159) (Active) protein (His tag,AVI tag,Biotin)TSLP 宿主: 人 宿主: HEK-293 Cells Recombinant >85 % as determined by SDS-PAGE. Active
Thymic Stromal Lymphopoietin (TSLP) (Active) proteinTSLP 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Thymic Stromal Lymphopoietin (TSLP) protein (Fc Tag)TSLP 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
- 储存条件
- 4 °C
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- 抗原
- Thymic Stromal Lymphopoietin (TSLP)
- Abstract
- TSLP 产品
- 别名
- TSLP Protein, thymic stromal lymphopoietin Protein, TSLP Protein, Tslp Protein
- 背景
- TSLP is a hemopoietic protein that is expressed in the heart, liver and prostate. TSLP overlaps biological activities with IL-7 and binds with the heterodimeric receptor complex consisting of the IL-7R alpha chain (IL-7Rª) and the TSLP-specific chain (TSLPR). Like IL-7, TSLP induces phosphorylation of STAT3 and STAT5, but uses kinases other than the JAKs for activation. TSLP prohibited apoptosis and stimulated growth of the human acute myeloid leukemia (AML)-derived cell line MUTZ3. It induces the release of T cell-attracting chemokines TARC and MDC from monocytes and activates CD11c(+) dendritic cells (DCs). TSLP activated DCs primed naive T cells to produce the proallergic cytokines (IL-4, IL-5, IL-13, TNFª) while down-regulating IL-10 and IFN-γ suggesting a role in initiating allergic inflammation. Synonym: Thymic Stromal Lymphopoietin ( TSLP), Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 150mM NaCl.
- 分子量
- Approximately 15.0 KDa, a single non-glycosylated polypeptide chain containing 132 amino acids.
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