CCL25 蛋白
Quick Overview for CCL25 蛋白 (ABIN988253)
抗原
See all CCL25 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- QGVFEDCCLA YHYPIGWAVL RRAWTYRIQE VSGSCNLPAA IFYLPKRHRK VCGNPKSREV QRAMKLLDAR NKVFAKLHHN MQTFQAGPHA VKKLSSGNSK LSSSKFSNPI SSSRKNVSLL ISANSG
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产品特性
- Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human monocytes is less than 10 ng/ml, corresponding to a specific activity of >, 1.0 × 105 IU/mg.
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内毒素水平
- Level Less than 1EU/µg of rHuTECK/CCL25 as determined by LAL method
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Chemokine (C-C Motif) Ligand 25 (CCL25) (Transcript Variant 1) (Active) protein
CCL25 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining Func, AbP, PI, STD Active
Chemokine (C-C Motif) Ligand 25 (CCL25) (AA 24-150) protein (GST tag)CCL25 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at
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储存条件
- 4 °C
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- CCL25 (Chemokine (C-C Motif) Ligand 25 (CCL25))
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别名
- TECK/CCL25
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背景
- CCL25 (thymus expressed chemokine) is a novel CC chemokine that is distantly related (approximately 20% amino acid sequence identity) to other CC chemokines. Mouse CCL25 cDNA has also been cloned and shown to encode a 144 aa protein that exhibits 49% aa sequence identity to human CCL25. The expresssion of human and mouse CCL25 was shown to be highly restricted to the thymus and small intestine. Although dendritic cells have been demonstrated to be the source of CCL25 production in the thymus, dendritic cells derived from bone marrow do not express CCL25. Recombinant human and mouse CCL25 have been shown to be chemotactic for activated macrophages, dendritic cells and thymocytes. CCL25 signals through the CCR9 receptor. Synonym: TECK/CCL25, Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 150mM NaCl.
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分子量
- 14.2 kDa, a single, non-glycosylated polypeptide chain containing 127 amino acids.
抗原
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