CXCL9 蛋白
This CXCL9 protein is expressed in 大肠杆菌（E. Coli）.
Quick Overview for CXCL9 蛋白 (ABIN988151)
抗原
See all CXCL9 蛋白
CXCL9
(gamma-Interferon-Induced Monokine (CXCL9))
生物活性
Active
宿主
人
资源
大肠杆菌（E. Coli）
纯度
> 97 % by SDS-PAGE and HPLC analyses.
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序列
- TPVVRKGRCS CISTNQGTIH LQSLKDLKQF APSPSCEKIE IIATLKNGVQ TCLNPDSADV KELIKKWEKQ VSQKKKQKNG KKHQKKKVLK VRKSQRSRQK KT
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产品特性
- Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human peripheral blood T-lymphocytes is less than 100 ng/ml, corresponding to a specific activity of >, 1.0 × 104 IU/mg.
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内毒素水平
- Level Less than 1EU/µg of rHuMIG/CXCL9 as determined by LAL method
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gamma-Interferon-Induced Monokine (CXCL9) protein (Fc Tag)
CXCL9 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
gamma-Interferon-Induced Monokine (CXCL9) (AA 23-125) protein (GST tag)CXCL9 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
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储存条件
- 4 °C
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- CXCL9 (gamma-Interferon-Induced Monokine (CXCL9))
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别名
- MIG/CXCL9
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背景
- CXCL9, a member of the ª subfamily of chemokines that lack the ELR domain, was initially identified as a lymphokine-activated gene in mouse macrophages. The CXCL9 gene is induced in macrophages and in primary glial cells of the central nervous system specifically in response to IFN-γ. CXCL9 has been shown to be a chemoattractant for activated T-lymphocytes and TIL but not for neutrophils or monocytes. The human CXCL9 cDNA encodes a 125 amino acid residue precursor protein with a 22 amino acid residue signal peptide that is cleaved to yield a 103 amino acid residue mature protein. CXCL9 has an extended carboxy-terminus containing greater than 50% basic amino acid residues and is larger than most other chemokines. A chemokine receptor (CXCR3) specific for CXCL9 and IP-10 has recently been cloned and shown to be highly expressed in IL-2-activated T-lymphocytes. Synonym: MIG/CXCL9, Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 50mM NaCl.
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分子量
- 11.7 kDa, a single non-glycosylated polypeptide chain containing 103 amino acids.
抗原
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